A9NHW6 (GCP_ACHLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	ACL_1354

Organism

Acholeplasma laidlawii (strain PG-8A) [Complete proteome] [HAMAP]

Taxonomic identifier

441768 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Acholeplasma

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000145937

Sequences

	Sequence		Length	Mass (Da)
	A9NHW6 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3DF39A06820DC765	FASTA	331	35,813
	10 20 30 40 50 60 MIILSVETSC DETSVAITKD GKTVLSNAVL SQIKIHQPYG GVVPEIASRA HIESMLYMFD 70 80 90 100 110 120 KAIKDAGIKV SDIDLVAVTQ GPGLIGSLLV GINAATTFAY ANQIPLMGVN HLLGHIYAAQ 130 140 150 160 170 180 IEGEMKFPLL TLLVSGGHTE LLLVKDHLEI ELLGTTLDDA VGEAYDKVAR MLGLGYPGGP 190 200 210 220 230 240 VVDRLAHQGE AIYNLPKPFL KNEPFNFSFS GLKSSVLNLV HNMKQRNEPF KVEDVCASFQ 250 260 270 280 290 300 ESVTEVLVQK TKDAANNLGV KQIVVAGGVA ANKGLRTKMK ERITDLEILT PSIKYCTDQA 310 320 330 AMIGIAAYYQ FKKQGALKDY YLKGSSAINF I

References

[1]

"Complete genome and proteome of Acholeplasma laidlawii." Lazarev V.N., Levitskii S.A., Basovskii Y.I., Chukin M.M., Akopian T.A., Vereshchagin V.V., Kostrjukova E.S., Kovaleva G.Y., Kazanov M.D., Malko D.B., Vitreschak A.G., Sernova N.V., Gelfand M.S., Demina I.A., Serebryakova M.V., Galyamina M.A., Vtyurin N.N., Rogov S.I. , Alexeev D.G., Ladygina V.G., Govorun V.M. J. Bacteriol. 193:4943-4953(2011) [PubMed: 21784942] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PG-8A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000896 Genomic DNA. Translation: ABX81946.1.
RefSeq	YP_001621322.1. NC_010163.1.
3D structure databases
ProteinModelPortal	A9NHW6.
ModBase	Search...
Protein-protein interaction databases
STRING	A9NHW6.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5803790.
GenomeReviews	Gene locus ACL_1354 in contig CP000896_GR.
KEGG	acl:ACL_1354.
PATRIC	20639398. VBIAchLai134690_1299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	ALAI441768:ACL_1354-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_ACHLI

Accession

Primary (citable) accession number: A9NHW6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program