Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60 kDa chaperonin

Gene

groL

Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:ACL_1247
OrganismiAcholeplasma laidlawii (strain PG-8A)
Taxonomic identifieri441768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
Proteomesi
  • UP000008558 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000824601 – 53660 kDa chaperoninAdd BLAST536

Proteomic databases

PRIDEiA9NHL6.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi441768.ACL_1247.

Structurei

3D structure databases

ProteinModelPortaliA9NHL6.
SMRiA9NHL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.

Sequencei

Sequence statusi: Complete.

A9NHL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKEIRYGKD AKQSLLKGVD LLANTVKITL GPKGRNVVLD KGYGSPLITN
60 70 80 90 100
DGVSIAKEIE LKDPYENMGA KLLYEVASKT NDVAGDGTTT ATLLAQSIIH
110 120 130 140 150
KGFKAVDNGA NPVLVREGIL RAGKEVSQKL LEKSRPVETS EDIENVASIS
160 170 180 190 200
ASSREIGKII AEAMDKVSKN GVISVDESKG FETELEVVEG MQYDKGYISP
210 220 230 240 250
YFVSDRETMT VELENPHVLV TDQKISTIQD ILPILEQVVK ANKPLLIIAD
260 270 280 290 300
DIENEVTSTL ILNKLRGTFN VVATKAPGFG DNQKDMLNDI AILTGATFYA
310 320 330 340 350
KDLQMKLQEI KLEDLGLVQK AVVKKDTTTL IGGHGTKDAI DKRILEIEAQ
360 370 380 390 400
INSSTSDYDK KRLQERLAKL AGGVAIIKVG AATEAELKEK KLRIEDALNA
410 420 430 440 450
TKAAILEGIV AGGGSVLVDI QTELKETLKD SHIDIYKGIL AVLDSLSEPL
460 470 480 490 500
YQIAENAGFD GQDILTEQRK QNKNYGFDAK EGKWVNMLKE GIIDPTKVTR
510 520 530
NAILNASSIG ALMITSEAAV VEIKDKDQNI PTQPMY
Length:536
Mass (Da):58,267
Last modified:February 5, 2008 - v1
Checksum:i23ED94C2EAA69C52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000896 Genomic DNA. Translation: ABX81846.1.
RefSeqiWP_012243177.1. NC_010163.1.

Genome annotation databases

EnsemblBacteriaiABX81846; ABX81846; ACL_1247.
KEGGiacl:ACL_1247.

Similar proteinsi

Entry informationi

Entry nameiCH60_ACHLI
AccessioniPrimary (citable) accession number: A9NHL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: June 7, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families