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A9NHH8

- PGK_ACHLI

UniProt

A9NHH8 - PGK_ACHLI

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Protein
Phosphoglycerate kinase
Gene
pgk, ACL_1209
Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei157 – 1571Substrate By similarity
Binding sitei208 – 2081ATP By similarity
Binding sitei296 – 2961ATP; via carbonyl oxygen By similarity
Binding sitei327 – 3271ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3584ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciALAI441768:GI40-1209-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:ACL_1209
OrganismiAcholeplasma laidlawii (strain PG-8A)
Taxonomic identifieri441768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
ProteomesiUP000008558: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Phosphoglycerate kinaseUniRule annotation
PRO_1000076578Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi441768.ACL_1209.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni60 – 634Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

A9NHH8-1 [UniParc]FASTAAdd to Basket

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MAKKTIRDIE LKNKSVLMRV DFNVPLNKDG SISDDTRITA ALPTIEYAIE    50
KGAKLILFSH LGRIKTAEDK ATNSLKPVAA RLSELIGRPV VFIPETRGEA 100
LEAAVKNLKS GDVLMFENTR FEDLDGNKES KNNPELGKYW ASLGDVFVND 150
AFGTAHRAHA SNVGIANNME VSVAGLLLEK EINFIGGALE NPERPFVAIL 200
GGAKVSDKIE VIKNLLKVAD KVLIGGGMAF TFLKAQGFEV GKSLVELDKL 250
DLAKELLELS KGKIELGFDV VTGKAFDKDT ETNVRSFDAI PADEMGLDIG 300
PKTVARFKEI IASAKTVVWN GPQGVFEMEK FANGTLEVTK ALADLHGKAI 350
TIVGGGDSAA AVAKFGLEDK FSHISTGGGA SLEYLEGKVL PGVELVDVI 399
Length:399
Mass (Da):42,767
Last modified:February 5, 2008 - v1
Checksum:i437BA8B2468A40D6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000896 Genomic DNA. Translation: ABX81808.1.
RefSeqiYP_001621184.1. NC_010163.1.

Genome annotation databases

EnsemblBacteriaiABX81808; ABX81808; ACL_1209.
GeneIDi5803962.
KEGGiacl:ACL_1209.
PATRICi20639116. VBIAchLai134690_1164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000896 Genomic DNA. Translation: ABX81808.1 .
RefSeqi YP_001621184.1. NC_010163.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 441768.ACL_1209.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX81808 ; ABX81808 ; ACL_1209 .
GeneIDi 5803962.
KEGGi acl:ACL_1209.
PATRICi 20639116. VBIAchLai134690_1164.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci ALAI441768:GI40-1209-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PG-8A.

Entry informationi

Entry nameiPGK_ACHLI
AccessioniPrimary (citable) accession number: A9NHH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: June 11, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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