deoB

Functionⁱ

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotation

Catalytic activityⁱ

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotation

2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotation

Cofactorⁱ

Mn²⁺UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayⁱ: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

Phosphopentomutase (deoB)
no protein annotated in this organism
no protein annotated in this organism

This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	12	ManganeseUniRule annotation	1
Metal bindingⁱ	296	ManganeseUniRule annotation	1
Metal bindingⁱ	332	ManganeseUniRule annotation	1
Metal bindingⁱ	333	ManganeseUniRule annotation	1
Metal bindingⁱ	344	ManganeseUniRule annotation	1

GO - Molecular functionⁱ

magnesium ion binding Source: InterPro
phosphopentomutase activity Source: UniProtKB-EC

Complete GO annotation...

GO - Biological processⁱ

5-phosphoribose 1-diphosphate biosynthetic process Source: UniProtKB-UniPathway
cellular metabolic compound salvage Source: InterPro
nucleotide metabolic process Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	Isomerase
Ligand	Manganese, Metal-binding

Enzyme and pathway databases

UniPathwayⁱ	UPA00087; UER00173.

UniPathwayⁱ

UPA00087; UER00173.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: PhosphopentomutaseUniRule annotation (EC:5.4.2.7UniRule annotation) Alternative name(s): PhosphodeoxyribomutaseUniRule annotation
Gene namesⁱ	Name:deoBUniRule annotation Ordered Locus Names:ACL_0680
Organismⁱ	Acholeplasma laidlawii (strain PG-8A)
Taxonomic identifierⁱ	441768 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Acholeplasma › Acholeplasma laidlawii
Proteomesⁱ	UP000008558 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00740

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000133054	1 – 397	PhosphopentomutaseAdd BLAST		397

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	441768.ACL_0680.

STRINGⁱ

441768.ACL_0680.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A9NG16.
SMRⁱ	A9NG16.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the phosphopentomutase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105CZG. Bacteria. COG1015. LUCA.
HOGENOMⁱ	HOG000008159.
KEGG Orthology (KO) More...KOⁱ	K01839.
OMAⁱ	CHASGTE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00WE.

Family and domain databases

Gene3Dⁱ	3.30.70.1250. 1 hit. 3.40.720.10. 1 hit.
HAMAPⁱ	MF_00740. Phosphopentomut. 1 hit.
InterProⁱ	View protein in InterPro IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR010045. DeoB. IPR006124. Metalloenzyme. IPR024052. Phosphopentomutase_DeoB_cap.
PANTHERⁱ	PTHR21110. PTHR21110. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01676. Metalloenzyme. 1 hit.
PIRSFⁱ	PIRSF001491. Ppentomutase. 1 hit.
SUPFAMⁱ	SSF143856. SSF143856. 1 hit. SSF53649. SSF53649. 2 hits.
TIGRFAMsⁱ	TIGR01696. deoB. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A9NG16-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRFKRVFLIV MDSLGVGASE DANQYFNEGV DDTKANTFGH IAESMDLRIP 
        60         70         80         90        100
NLEKLGVGNI IPIKGTKSVE LSSSYVTKIR EKSLGKDTMT GHWEIMGLYV 
       110        120        130        140        150
TTPFQTFTDT GFPKELLDEL EERTGRKIIG NIAASGTEIL KDLGEEHMRT 
       160        170        180        190        200
GDLIVYTSAD SVLQIAMHEE IIPIEEQYRI SAIARDITMR PDWKVGRVIT 
       210        220        230        240        250
RPFLGTNKDN FKRTSNRKDY ALKPSEETTL NFLSDANYDV IALGKINDIF 
       260        270        280        290        300
DGYGINKYSK TVSNDDGMKQ ITEWAKKDFT GLCFLNLVDF DALYGHRRDP 
       310        320        330        340        350
HGYGKAIMDM DSQLPELMAN LNEDDLLILT ADHGNDPTYV GTDHTREFVP 
       360        370        380        390 
MIAYSKSFKS GGSLPILNTF ADLGSTISDN FKVKKTEHGD SFLSKLK

Length:397

Mass (Da):44,505

Last modified:February 5, 2008 - v1

Checksum:ⁱ58CE487E95F8CB5C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000896 Genomic DNA. Translation: ABX81296.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_012242627.1. NC_010163.1.

Genome annotation databases

EnsemblBacteriaⁱ	ABX81296; ABX81296; ACL_0680.
KEGGⁱ	acl:ACL_0680.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000896 Genomic DNA. Translation: ABX81296.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_012242627.1. NC_010163.1.

3D structure databases

ProteinModelPortalⁱ	A9NG16.
SMRⁱ	A9NG16.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	441768.ACL_0680.

STRINGⁱ

441768.ACL_0680.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ABX81296; ABX81296; ACL_0680.
KEGGⁱ	acl:ACL_0680.

Phylogenomic databases

eggNOGⁱ	ENOG4105CZG. Bacteria. COG1015. LUCA.
HOGENOMⁱ	HOG000008159.
KEGG Orthology (KO) More...KOⁱ	K01839.
OMAⁱ	CHASGTE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00WE.

Enzyme and pathway databases

UniPathwayⁱ	UPA00087; UER00173.

UniPathwayⁱ

UPA00087; UER00173.

Family and domain databases

Gene3Dⁱ	3.30.70.1250. 1 hit. 3.40.720.10. 1 hit.
HAMAPⁱ	MF_00740. Phosphopentomut. 1 hit.
InterProⁱ	View protein in InterPro IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR010045. DeoB. IPR006124. Metalloenzyme. IPR024052. Phosphopentomutase_DeoB_cap.
PANTHERⁱ	PTHR21110. PTHR21110. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01676. Metalloenzyme. 1 hit.
PIRSFⁱ	PIRSF001491. Ppentomutase. 1 hit.
SUPFAMⁱ	SSF143856. SSF143856. 1 hit. SSF53649. SSF53649. 2 hits.
TIGRFAMsⁱ	TIGR01696. deoB. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DEOB_ACHLI
Accessionⁱ	A9NG16Primary (citable) accession number: A9NG16
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
	Last sequence update:	February 5, 2008
	Last modified:	June 7, 2017
	This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A9NG16 (DEOB_ACHLI)

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Phosphopentomutase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

Pathwayⁱ: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ