Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphopentomutase

Gene

deoB

Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotation
2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotation

Cofactori

Mn2+UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Phosphopentomutase (deoB)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi12ManganeseUniRule annotation1
Metal bindingi296ManganeseUniRule annotation1
Metal bindingi332ManganeseUniRule annotation1
Metal bindingi333ManganeseUniRule annotation1
Metal bindingi344ManganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyciALAI441768:G1GAM-693-MONOMER
UniPathwayiUPA00087; UER00173

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphopentomutaseUniRule annotation (EC:5.4.2.7UniRule annotation)
Alternative name(s):
PhosphodeoxyribomutaseUniRule annotation
Gene namesi
Name:deoBUniRule annotation
Ordered Locus Names:ACL_0680
OrganismiAcholeplasma laidlawii (strain PG-8A)
Taxonomic identifieri441768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
Proteomesi
  • UP000008558 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001330541 – 397PhosphopentomutaseAdd BLAST397

Interactioni

Protein-protein interaction databases

STRINGi441768.ACL_0680

Structurei

3D structure databases

ProteinModelPortaliA9NG16
SMRiA9NG16
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphopentomutase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CZG Bacteria
COG1015 LUCA
HOGENOMiHOG000008159
KOiK01839
OMAiCHASGTE
OrthoDBiPOG091H00WE

Family and domain databases

CDDicd16009 PPM, 1 hit
Gene3Di3.30.70.12501 hit
3.40.720.102 hits
HAMAPiMF_00740 Phosphopentomut, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR010045 DeoB
IPR006124 Metalloenzyme
IPR024052 Phosphopentomutase_DeoB_cap_sf
PANTHERiPTHR21110 PTHR21110, 1 hit
PfamiView protein in Pfam
PF01676 Metalloenzyme, 1 hit
PIRSFiPIRSF001491 Ppentomutase, 1 hit
SUPFAMiSSF143856 SSF143856, 1 hit
SSF53649 SSF53649, 2 hits
TIGRFAMsiTIGR01696 deoB, 1 hit

Sequencei

Sequence statusi: Complete.

A9NG16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFKRVFLIV MDSLGVGASE DANQYFNEGV DDTKANTFGH IAESMDLRIP
60 70 80 90 100
NLEKLGVGNI IPIKGTKSVE LSSSYVTKIR EKSLGKDTMT GHWEIMGLYV
110 120 130 140 150
TTPFQTFTDT GFPKELLDEL EERTGRKIIG NIAASGTEIL KDLGEEHMRT
160 170 180 190 200
GDLIVYTSAD SVLQIAMHEE IIPIEEQYRI SAIARDITMR PDWKVGRVIT
210 220 230 240 250
RPFLGTNKDN FKRTSNRKDY ALKPSEETTL NFLSDANYDV IALGKINDIF
260 270 280 290 300
DGYGINKYSK TVSNDDGMKQ ITEWAKKDFT GLCFLNLVDF DALYGHRRDP
310 320 330 340 350
HGYGKAIMDM DSQLPELMAN LNEDDLLILT ADHGNDPTYV GTDHTREFVP
360 370 380 390
MIAYSKSFKS GGSLPILNTF ADLGSTISDN FKVKKTEHGD SFLSKLK
Length:397
Mass (Da):44,505
Last modified:February 5, 2008 - v1
Checksum:i58CE487E95F8CB5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000896 Genomic DNA Translation: ABX81296.1
RefSeqiWP_012242627.1, NC_010163.1

Genome annotation databases

EnsemblBacteriaiABX81296; ABX81296; ACL_0680
KEGGiacl:ACL_0680

Similar proteinsi

Entry informationi

Entry nameiDEOB_ACHLI
AccessioniPrimary (citable) accession number: A9NG16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome