deoB

Functionⁱ

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotation

Catalytic activityⁱ

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotation

2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotation

Cofactorⁱ

Mn²⁺UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayⁱ: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

Phosphopentomutase (deoB)
no protein annotated in this organism
no protein annotated in this organism

This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	12	ManganeseUniRule annotation	1
Metal bindingⁱ	296	ManganeseUniRule annotation	1
Metal bindingⁱ	332	ManganeseUniRule annotation	1
Metal bindingⁱ	333	ManganeseUniRule annotation	1
Metal bindingⁱ	344	ManganeseUniRule annotation	1

GO - Molecular functionⁱ

magnesium ion binding Source: InterPro
phosphopentomutase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

5-phosphoribose 1-diphosphate biosynthetic process Source: UniProtKB-UniPathway
cellular metabolic compound salvage Source: InterPro
nucleotide metabolic process Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Isomerase
Ligand	Manganese, Metal-binding

Enzyme and pathway databases

BioCycⁱ	ALAI441768:G1GAM-693-MONOMER
UniPathwayⁱ	UPA00087; UER00173

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: PhosphopentomutaseUniRule annotation (EC:5.4.2.7UniRule annotation) Alternative name(s): PhosphodeoxyribomutaseUniRule annotation
Gene namesⁱ	Name:deoBUniRule annotation Ordered Locus Names:ACL_0680
Organismⁱ	Acholeplasma laidlawii (strain PG-8A)
Taxonomic identifierⁱ	441768 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Acholeplasma › Acholeplasma laidlawii
Proteomesⁱ	UP000008558 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00740

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000133054	1 – 397	PhosphopentomutaseAdd BLAST		397

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	441768.ACL_0680

STRINGⁱ

441768.ACL_0680

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A9NG16
SMRⁱ	A9NG16
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the phosphopentomutase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105CZG Bacteria COG1015 LUCA
HOGENOMⁱ	HOG000008159
KEGG Orthology (KO) More...KOⁱ	K01839
OMAⁱ	CHASGTE
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00WE

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd16009 PPM, 1 hit
Gene3Dⁱ	3.30.70.12501 hit 3.40.720.102 hits
HAMAPⁱ	MF_00740 Phosphopentomut, 1 hit
InterProⁱ	View protein in InterPro IPR017849 Alkaline_Pase-like_a/b/a IPR017850 Alkaline_phosphatase_core_sf IPR010045 DeoB IPR006124 Metalloenzyme IPR024052 Phosphopentomutase_DeoB_cap_sf
PANTHERⁱ	PTHR21110 PTHR21110, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01676 Metalloenzyme, 1 hit
PIRSFⁱ	PIRSF001491 Ppentomutase, 1 hit
SUPFAMⁱ	SSF143856 SSF143856, 1 hit SSF53649 SSF53649, 2 hits
TIGRFAMsⁱ	TIGR01696 deoB, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A9NG16-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRFKRVFLIV MDSLGVGASE DANQYFNEGV DDTKANTFGH IAESMDLRIP 
        60         70         80         90        100
NLEKLGVGNI IPIKGTKSVE LSSSYVTKIR EKSLGKDTMT GHWEIMGLYV 
       110        120        130        140        150
TTPFQTFTDT GFPKELLDEL EERTGRKIIG NIAASGTEIL KDLGEEHMRT 
       160        170        180        190        200
GDLIVYTSAD SVLQIAMHEE IIPIEEQYRI SAIARDITMR PDWKVGRVIT 
       210        220        230        240        250
RPFLGTNKDN FKRTSNRKDY ALKPSEETTL NFLSDANYDV IALGKINDIF 
       260        270        280        290        300
DGYGINKYSK TVSNDDGMKQ ITEWAKKDFT GLCFLNLVDF DALYGHRRDP 
       310        320        330        340        350
HGYGKAIMDM DSQLPELMAN LNEDDLLILT ADHGNDPTYV GTDHTREFVP 
       360        370        380        390 
MIAYSKSFKS GGSLPILNTF ADLGSTISDN FKVKKTEHGD SFLSKLK

Length:397

Mass (Da):44,505

Last modified:February 5, 2008 - v1

Checksum:ⁱ58CE487E95F8CB5C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000896 Genomic DNA Translation: ABX81296.1
NCBI Reference Sequences More...RefSeqⁱ	WP_012242627.1, NC_010163.1

Genome annotation databases

EnsemblBacteriaⁱ	ABX81296; ABX81296; ACL_0680
KEGGⁱ	acl:ACL_0680

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A9NG16	A0A2G7QM99	Acholeplasma laidlawii	397	UniRef100_A9NG16	Cluster: Phosphopentomutase	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A9NG16	A0A2G7QM99 A0A2G7QIC0 UPI00084C6337	Acholeplasma laidlawii	397	UniRef90_A9NG16	Cluster: Phosphopentomutase	4

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A9NG16	Q894Z2 A0A1T4PNF9 A0A240A444 UPI000512EBFE A0A1G9J7K4 U6EVS0 UPI000BBBF299 R9N4U3 R9MEQ2 R6RSC5 +336	Clostridium tetani (strain Massachusetts / E88) Clostridium tetani Clostridium cochlearium Clostridium tetani 12124569 Dorea sp. 5-2 Lachnospiraceae bacterium 3-2 Clostridium sp. CAG:58 Lachnospiraceae bacterium M18-1 Acholeplasma laidlawii Geobacillus sp. (strain C56-T3) And more	398	UniRef50_Q894Z2	Cluster: Phosphopentomutase	347

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000896 Genomic DNA Translation: ABX81296.1
NCBI Reference Sequences More...RefSeqⁱ	WP_012242627.1, NC_010163.1

3D structure databases

ProteinModelPortalⁱ	A9NG16
SMRⁱ	A9NG16
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	441768.ACL_0680

STRINGⁱ

441768.ACL_0680

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ABX81296; ABX81296; ACL_0680
KEGGⁱ	acl:ACL_0680

Phylogenomic databases

eggNOGⁱ	ENOG4105CZG Bacteria COG1015 LUCA
HOGENOMⁱ	HOG000008159
KEGG Orthology (KO) More...KOⁱ	K01839
OMAⁱ	CHASGTE
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00WE

Enzyme and pathway databases

UniPathwayⁱ	UPA00087; UER00173
BioCycⁱ	ALAI441768:G1GAM-693-MONOMER

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd16009 PPM, 1 hit
Gene3Dⁱ	3.30.70.12501 hit 3.40.720.102 hits
HAMAPⁱ	MF_00740 Phosphopentomut, 1 hit
InterProⁱ	View protein in InterPro IPR017849 Alkaline_Pase-like_a/b/a IPR017850 Alkaline_phosphatase_core_sf IPR010045 DeoB IPR006124 Metalloenzyme IPR024052 Phosphopentomutase_DeoB_cap_sf
PANTHERⁱ	PTHR21110 PTHR21110, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01676 Metalloenzyme, 1 hit
PIRSFⁱ	PIRSF001491 Ppentomutase, 1 hit
SUPFAMⁱ	SSF143856 SSF143856, 1 hit SSF53649 SSF53649, 2 hits
TIGRFAMsⁱ	TIGR01696 deoB, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DEOB_ACHLI
Accessionⁱ	A9NG16Primary (citable) accession number: A9NG16
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
	Last sequence update:	February 5, 2008
	Last modified:	February 28, 2018
	This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A9NG16 (DEOB_ACHLI)

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Phosphopentomutase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ