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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotationImported
Ordered Locus Names:ACL_0550Imported
OrganismiAcholeplasma laidlawii (strain PG-8A)Imported
Taxonomic identifieri441768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
Proteomesi
  • UP000008558 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei177Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

PhosphoproteinUniRule annotation

Proteomic databases

PRIDEiA9NFN8.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi441768.ACL_0550.

Structurei

3D structure databases

ProteinModelPortaliA9NFN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili226 – 253Sequence analysisAdd BLAST28
Coiled coili483 – 512Sequence analysisAdd BLAST30
Coiled coili529 – 563Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228137.
KOiK04043.
OMAiISIKRHM.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiView protein in InterPro
IPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C_sf.
IPR029047. HSP70_peptide-bd_sf.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A9NFN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKTNKIIGI DLGTTNSVVS VMEGNEAKVI PNAEGGRTTP SIVAFKGDEI
60 70 80 90 100
LVGEVAKRQL ITNPDTIYSI KRHMGDLNYK VKAAGKEFTP QQISAYILQN
110 120 130 140 150
LKKTAEDYLG ATVTEAVITV PAYFNDAQRQ ATKDAGTIAG LNVRRIINEP
160 170 180 190 200
TASALAYGID KTDKEQTILV FDLGGGTFDV SILHLADGTF EVVSTSGDNK
210 220 230 240 250
LGGDDFDHKI YEFLAAEFNK EHGIDLLKDK MALQRLRDAA EKAKKELSGV
260 270 280 290 300
TTSSISLPFI TMGAAGPLHF EYNLTRAKFN ELTKDLVDRT MVSVRRALAD
310 320 330 340 350
AKLTNSDINQ ILLVGGSTRI PAVQELVTKE FGKEPNRSVN PDEVVAMGAA
360 370 380 390 400
IQGAVLAGDV KDVLLLDVTP LSLGIETLGG VATRLIERNT TIPTSKSQVF
410 420 430 440 450
STAADNQPAV DIHVLQGERP MAADNKTLGR FQLTDIPPAR RGVPQIEVTF
460 470 480 490 500
DIDANGIVSV KAKDLGTNKE QKITISGNGG LSKEEIDAMI KQAEENAEAD
510 520 530 540 550
NKRKESADAR NEADSMIFQS RKAIEDLGAE VTDEEKETVE NAIKDLEEAL
560 570 580 590 600
KGDDVEAIKA KNEALAKASQ SIAMKAYEKA NKSNGSDVNG ATDADDNKDD
610
AVEAEFTEKQ
Length:610
Mass (Da):65,683
Last modified:February 5, 2008 - v1
Checksum:i1FE37DC375DAC040
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000896 Genomic DNA. Translation: ABX81168.1.
RefSeqiWP_012242499.1. NC_010163.1.

Genome annotation databases

EnsemblBacteriaiABX81168; ABX81168; ACL_0550.
KEGGiacl:ACL_0550.

Similar proteinsi

Entry informationi

Entry nameiA9NFN8_ACHLI
AccessioniPrimary (citable) accession number: A9NFN8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 22, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported