A9NFF6 (FENR_ACHLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2

Gene names

Ordered Locus Names:

ACL_0467

Organism

Acholeplasma laidlawii (strain PG-8A) [Complete proteome] [HAMAP]

Taxonomic identifier

441768 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Acholeplasma

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.
Sequence caution	The sequence ABX81086.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 322	322	Ferredoxin--NADP reductase HAMAP MF_01685		PRO_0000364777
Sites
	Binding site	12	1	FAD By similarity
	Binding site	31	1	FAD By similarity
	Binding site	39	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	86	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	119	1	FAD; via amide nitrogen By similarity
	Binding site	317	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9NFF6 [UniParc]. Last modified March 3, 2009. Version 2. Checksum: 19D1821609F9E7CF	FASTA	322	36,026
	10 20 30 40 50 60 MLEVLIIGAG PTGLYAAFLA GLRNLKAAVI ESSAEPGGQL TAVYKDKYIY DIPGFPKITA 70 80 90 100 110 120 KDYIDGQVLQ YERFKSDLPI YYNEEAIDIK KHDDHFIVTT TTKTIETKFV LIAHGGGGFV 130 140 150 160 170 180 PQKLKIDEHY DNILYFIKDL NQFKDKKIVV LGGGDSALDW AIDLSEYTKD VTLVHRRDEF 190 200 210 220 230 240 RALQSSVDHF REKGTILTPY IVDTVEGNDK LVHTLVLKHA KTHERLNLDA DYIVVNYGFV 250 260 270 280 290 300 LTKSRLDEWG IEGEKGLIKV DYTMKTSLDG IYAAGNGIDY PGKVKLISTG QGEAATAIQS 310 320 ITTLLYPEKT RKFEHSTALI KE

References

[1]

"Complete genome and proteome of Acholeplasma laidlawii." Lazarev V.N., Levitskii S.A., Basovskii Y.I., Chukin M.M., Akopian T.A., Vereshchagin V.V., Kostrjukova E.S., Kovaleva G.Y., Kazanov M.D., Malko D.B., Vitreschak A.G., Sernova N.V., Gelfand M.S., Demina I.A., Serebryakova M.V., Galyamina M.A., Vtyurin N.N., Rogov S.I. , Alexeev D.G., Ladygina V.G., Govorun V.M. J. Bacteriol. 193:4943-4953(2011) [PubMed: 21784942] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PG-8A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000896 Genomic DNA. Translation: ABX81086.1. Different initiation.
RefSeq	YP_001620462.1. NC_010163.1.
3D structure databases
ProteinModelPortal	A9NFF6.
ModBase	Search...
Protein-protein interaction databases
STRING	A9NFF6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5803142.
GenomeReviews	Gene locus ACL_0467 in contig CP000896_GR.
KEGG	acl:ACL_0467.
PATRIC	20637654. VBIAchLai134690_0448.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG669726.
Enzyme and pathway databases
BioCyc	ALAI441768:ACL_0467-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR_ACHLI

Accession

Primary (citable) accession number: A9NFF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 32 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program