Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A9NEN3

- EFG_ACHLI

UniProt

A9NEN3 - EFG_ACHLI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Elongation factor G

Gene

fusA

Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 248GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi135 – 1384GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciALAI441768:GI40-187-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor GUniRule annotation
Short name:
EF-GUniRule annotation
Gene namesi
Name:fusAUniRule annotation
Ordered Locus Names:ACL_0187
OrganismiAcholeplasma laidlawii (strain PG-8A)
Taxonomic identifieri441768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
ProteomesiUP000008558: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 690690Elongation factor GPRO_1000074945Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi441768.ACL_0187.

Structurei

3D structure databases

ProteinModelPortaliA9NEN3.
SMRiA9NEN3. Positions 4-685.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 282275tr-type GAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0480.
HOGENOMiHOG000231585.
KOiK02355.
OMAiSGVQPQT.
OrthoDBiEOG6X6RBF.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00054_B. EF_G_EF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004540. Transl_elong_EFG/EF2.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00484. EF-G. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9NEN3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPRQYSLKMT RNIGIMAHID AGKTTTTERI LFHTGKIHKT GETHDGASQM
60 70 80 90 100
DWMAQEQERG ITITSAATTS VWRDHRVNII DTPGHVDFTV EVSRSLRVLD
110 120 130 140 150
GAVTVIDAQA GVEPQTETVW RQATEYKVPR IVYVNKMDKI GADFNNAIKT
160 170 180 190 200
LHRRLGVKAN AIQLPIGTEL DFSGIIDLVT MTAVEYSGDA LETTKEIPIP
210 220 230 240 250
AHLEEQAIDM RNELIEAVAE FDDELMVTYL EGEEVSVELL KRAIRKGVLA
260 270 280 290 300
VEFFPVVAGS SFKNKGVRKV LDAVIDYLPS PLDIPPVLGH TSEGVEVYRH
310 320 330 340 350
ADDEEPFTAL AFKVMTDPFV GKLTFFRVYS GKIKSGSYVQ NTTKGERERF
360 370 380 390 400
GRILQMHANT RQEIDEVYAG DIAAAVGLKV TTTGNTLATQ NDDIILESMN
410 420 430 440 450
FPEPVIEVAV EPKTKNDQDK MGQALAKLAE EDPTFKTYTN TETGQTIIAG
460 470 480 490 500
MGELHLDILV DRMKREFKVE ANVTEPQVSY RETLTVPNEI EAKFIRQSGG
510 520 530 540 550
RGQYGHVVID FEPNPGKGFE FVDKIVGGVI PREYIPSVQK GLEEALGGGI
560 570 580 590 600
LAGFPVVDIK ATLKFGSYHD VDSSEMAYKI AASMALKDAK NKANAVILEP
610 620 630 640 650
IMDVEVVTPN DYVGNVIGDI TSRRGRLESQ EGRGNAISIR AFVPLSEMFG
660 670 680 690
YATSLRSNTQ GRATFVMQFD HFDKVPKSIQ EEIIKKRGSN
Length:690
Mass (Da):76,335
Last modified:February 5, 2008 - v1
Checksum:iDAC5F17833FDCF3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000896 Genomic DNA. Translation: ABX80813.1.
RefSeqiYP_001620189.1. NC_010163.1.

Genome annotation databases

EnsemblBacteriaiABX80813; ABX80813; ACL_0187.
GeneIDi5804183.
KEGGiacl:ACL_0187.
PATRICi20637084. VBIAchLai134690_0169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000896 Genomic DNA. Translation: ABX80813.1 .
RefSeqi YP_001620189.1. NC_010163.1.

3D structure databases

ProteinModelPortali A9NEN3.
SMRi A9NEN3. Positions 4-685.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 441768.ACL_0187.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX80813 ; ABX80813 ; ACL_0187 .
GeneIDi 5804183.
KEGGi acl:ACL_0187.
PATRICi 20637084. VBIAchLai134690_0169.

Phylogenomic databases

eggNOGi COG0480.
HOGENOMi HOG000231585.
KOi K02355.
OMAi SGVQPQT.
OrthoDBi EOG6X6RBF.

Enzyme and pathway databases

BioCyci ALAI441768:GI40-187-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00054_B. EF_G_EF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004540. Transl_elong_EFG/EF2.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
Pfami PF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SMARTi SM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsi TIGR00484. EF-G. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PG-8A.

Entry informationi

Entry nameiEFG_ACHLI
AccessioniPrimary (citable) accession number: A9NEN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3