Reviewed, UniProtKB/Swiss-Prot A9NBI0 (UBIG_COXBR)

Names and origin

Protein names

Recommended name:
    3-demethylubiquinone-9 3-methyltransferase
    EC=2.1.1.64
Alternative name(s):
    3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
      Short name=DHHB methyltransferase

Gene names

Name:	ubiG
Ordered Locus Names:	COXBURSA331_A0458

Organism

Coxiella burnetii (strain RSA 331 / Henzerling II) [Complete proteome] [HAMAP]

Taxonomic identifier

360115 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9. HAMAP MF_00472
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_00472
Sequence similarities	Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Inferred from electronic annotation. Source: InterPro 3-demethylubiquinone-9 3-O-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 234	234	3-demethylubiquinone-9 3-methyltransferase HAMAP MF_00472		PRO_1000081218

Sequences

	Sequence		Length	Mass (Da)
	A9NBI0-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 28B2169D8B59AA45	FASTA	234	26,485
	10 20 30 40 50 60 MTLSEQNIDK EELAKFSDLA QDWWNPAGKM KPLHLINPVR LKYIEQQITL KGKHVLDVGC 70 80 90 100 110 120 GGGLLSEALA KHGAIVTGVD MSESLIDVAK NHAEQQQLNI NYQCQDIEIL TKDAQRFDII 130 140 150 160 170 180 TCMELLEHVP DPQRMIKNCA ALIKPGGKLF FSTINRNFKA YLYTIVGAEY VFNLLPKGTH 190 200 210 220 230 DYAQFIRPSE LTQWAESGGL RLLDITGIHY HPLKNEFDLS RDVSVNYLAC FTHE

References

[1]	"Genome sequencing of phylogenetically and phenotypically diverse Coxiella burnetii isolates." Seshadri R., Samuel J.E. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000890 Genomic DNA. Translation: ABX77424.1.
RefSeq	YP_001596294.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5793744.
GenomeReviews	Gene locus ubiG in contig CP000890_GR.
KEGG	cbs:COXBURSA331_A0458.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A9NBI0. ADIEYEC.
Family and domain databases
HAMAP	MF_00472. [Tree]
InterPro	IPR013216. Methyltransf_11. IPR010233. UbiG_MeTrfase. [Graphical view]
Pfam	PF08241. Methyltransf_11. 1 hit. [Graphical view]
TIGRFAMs	TIGR01983. UbiG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UBIG_COXBR

Accession

Primary (citable) accession number: A9NBI0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	June 16, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)