Reviewed,
UniProtKB/Swiss-Prot A9NBH0 (AROE_COXBR)
Last modified
June 16, 2009.
Version 14.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Shikimate dehydrogenase EC=1.1.1.25 | ||||
| Gene names |
| ||||
| Organism | Coxiella burnetii (strain RSA 331 / Henzerling II) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 360115 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella |
Protein attributes
| Sequence length | 272 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 4/7. HAMAP MF_00222 |
| Sequence similarities | Belongs to the shikimate dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: InterPro |
| Molecular function | NADP or NADPH binding Inferred from electronic annotation. Source: InterPro shikimate 5-dehydrogenase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 272 | 272 | Shikimate dehydrogenase HAMAP MF_00222 | PRO_1000078118 | |||||
Regions | |||||||||
| Nucleotide binding | 127 – 131 | 5 | NADP By similarity | ||||||
Sites | |||||||||
| Active site | 65 | 1 | Proton acceptor Potential | ||||||
Sequences
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References
| [1] | "Genome sequencing of phylogenetically and phenotypically diverse Coxiella burnetii isolates." Seshadri R., Samuel J.E. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000890 Genomic DNA. Translation: ABX77620.1. | |
| RefSeq | YP_001597801.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 5793247. |
| GenomeReviews | Gene locus aroE in contig CP000890_GR. |
| KEGG | cbs:COXBURSA331_A2191. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | A9NBH0. YDMMYGR. |
Family and domain databases | |
| HAMAP | MF_00222. [Tree] |
| InterPro | IPR016040. NAD(P)-bd_dom. IPR011342. Quinate/shikimate_5-DH. IPR013708. Shikimate_DH-bd_N. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| Pfam | PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00507. aroE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | AROE_COXBR | ||||||||
| Accession | Primary (citable) accession number: A9NBH0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


