Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A9NBA8 (MNMG_COXBR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Alternative name(s):
Glucose-inhibited division protein A
Gene names
Name:mnmG
Synonyms:gidA
Ordered Locus Names:COXBURSA331_A2125
OrganismCoxiella burnetii (strain RSA 331 / Henzerling II) [Complete proteome] [HAMAP]
Taxonomic identifier360115 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length627 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34 By similarity. HAMAP-Rule MF_00129

Cofactor

FAD By similarity. HAMAP-Rule MF_00129

Subunit structure

Homodimer By similarity. Heterotetramer of two MnmE and two MnmG subunits By similarity. HAMAP-Rule MF_00129

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00129.

Sequence similarities

Belongs to the MnmG family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandFAD
Flavoprotein
NAD
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA wobble uridine modification

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionflavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 627627tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG HAMAP-Rule MF_00129
PRO_1000076315

Regions

Nucleotide binding14 – 196FAD By similarity
Nucleotide binding274 – 28815NAD Potential

Sequences

Sequence LengthMass (Da)Tools
A9NBA8 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 6354640D5DB4837E

FASTA62769,969
        10         20         30         40         50         60 
MQSTSQQFDV IVVGGGHAGT EAALVAARMG ARTLLLTHNI ETLGQMSCNP AIGGIGKSHL 

        70         80         90        100        110        120 
VKEIDALGGI MALAADQAGI HFRTLNARKG PAVRATRAQA DRVLYKAAIH HALENQPHLW 

       130        140        150        160        170        180 
LFQQGVDDLI IQNNRAAGVV TQMGLAFYAP TVILTVGTFL GGKIHIGMNH YRGGRAGDPP 

       190        200        210        220        230        240 
ALALAERLRE MPFRVERLKT GTPPRIDGRT INYSQLIEQP SDQPLPLMSY WSHGEDRPRQ 

       250        260        270        280        290        300 
VSCFITQTNE KTHDIIRNGL KTSPLFSGVI EGVGPRYCPS IEDKIVRFAD RNSHQLFLEP 

       310        320        330        340        350        360 
EGLNTPEVYP NGVSTSLSFD VQLDFIHSIK GLEKCHITRP GYAIEYDYFD PRDLKPSLET 

       370        380        390        400        410        420 
KYVPGLYFAG QINGTTGYEE AAAQGLIAGI NAALQIQERA PWTPARDEAY IGVLIDDLTT 

       430        440        450        460        470        480 
RGTNEPYRMF TSRAEYRLLL RQDNADLRLT EKGRDLGCVD DERWNFFVKK KETIEKEQQR 

       490        500        510        520        530        540 
LKKQRIWPKS TVAKAIESRF QQLLERDYSA MDLLRRPEIN YPALMQIEEL GPAVLEPSVA 

       550        560        570        580        590        600 
EQIDIQAKYE GYLTHQLAEI ARQKKYQTAQ IPSSLDYNQV TGLSNEVRQK LNETKPTTLG 

       610        620 
QASRIPGITP AAISLLLVHL KKKELYP 

« Hide

References

[1]"Genome sequencing of phylogenetically and phenotypically diverse Coxiella burnetii isolates."
Seshadri R., Samuel J.E.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RSA 331 / Henzerling II.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000890 Genomic DNA. Translation: ABX78769.1.
RefSeqYP_001597739.1. NC_010117.1.

3D structure databases

ProteinModelPortalA9NBA8.
SMRA9NBA8. Positions 4-554.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360115.COXBURSA331_A2125.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX78769; ABX78769; COXBURSA331_A2125.
GeneID5792926.
KEGGcbs:COXBURSA331_A2125.
PATRIC17928486. VBICoxBur33747_2100.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0445.
HOGENOMHOG000201059.
KOK03495.
OMAYINGLST.
OrthoDBEOG6W9X6J.
ProtClustDBPRK05192.

Enzyme and pathway databases

BioCycCBUR360115:GI0X-2131-MONOMER.

Family and domain databases

HAMAPMF_00129. MnmG_GidA.
InterProIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00136. gidA. 1 hit.
PROSITEPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMNMG_COXBR
AccessionPrimary (citable) accession number: A9NBA8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families