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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Coxiella burnetii (strain RSA 331 / Henzerling II)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi14 – 196FADUniRule annotation
Nucleotide bindingi274 – 28815NADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciCBUR360115:GI0X-2131-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:COXBURSA331_A2125
OrganismiCoxiella burnetii (strain RSA 331 / Henzerling II)
Taxonomic identifieri360115 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 627627tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGPRO_1000076315Add
BLAST

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA9NBA8.
SMRiA9NBA8. Positions 4-554.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0445.
HOGENOMiHOG000201059.
KOiK03495.
OMAiFVEPEGW.
OrthoDBiEOG6W9X6J.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9NBA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSTSQQFDV IVVGGGHAGT EAALVAARMG ARTLLLTHNI ETLGQMSCNP
60 70 80 90 100
AIGGIGKSHL VKEIDALGGI MALAADQAGI HFRTLNARKG PAVRATRAQA
110 120 130 140 150
DRVLYKAAIH HALENQPHLW LFQQGVDDLI IQNNRAAGVV TQMGLAFYAP
160 170 180 190 200
TVILTVGTFL GGKIHIGMNH YRGGRAGDPP ALALAERLRE MPFRVERLKT
210 220 230 240 250
GTPPRIDGRT INYSQLIEQP SDQPLPLMSY WSHGEDRPRQ VSCFITQTNE
260 270 280 290 300
KTHDIIRNGL KTSPLFSGVI EGVGPRYCPS IEDKIVRFAD RNSHQLFLEP
310 320 330 340 350
EGLNTPEVYP NGVSTSLSFD VQLDFIHSIK GLEKCHITRP GYAIEYDYFD
360 370 380 390 400
PRDLKPSLET KYVPGLYFAG QINGTTGYEE AAAQGLIAGI NAALQIQERA
410 420 430 440 450
PWTPARDEAY IGVLIDDLTT RGTNEPYRMF TSRAEYRLLL RQDNADLRLT
460 470 480 490 500
EKGRDLGCVD DERWNFFVKK KETIEKEQQR LKKQRIWPKS TVAKAIESRF
510 520 530 540 550
QQLLERDYSA MDLLRRPEIN YPALMQIEEL GPAVLEPSVA EQIDIQAKYE
560 570 580 590 600
GYLTHQLAEI ARQKKYQTAQ IPSSLDYNQV TGLSNEVRQK LNETKPTTLG
610 620
QASRIPGITP AAISLLLVHL KKKELYP
Length:627
Mass (Da):69,969
Last modified:February 5, 2008 - v1
Checksum:i6354640D5DB4837E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000890 Genomic DNA. Translation: ABX78769.1.
RefSeqiWP_010958541.1. NC_010117.1.

Genome annotation databases

EnsemblBacteriaiABX78769; ABX78769; COXBURSA331_A2125.
KEGGicbs:COXBURSA331_A2125.
PATRICi17928486. VBICoxBur33747_2100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000890 Genomic DNA. Translation: ABX78769.1.
RefSeqiWP_010958541.1. NC_010117.1.

3D structure databases

ProteinModelPortaliA9NBA8.
SMRiA9NBA8. Positions 4-554.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX78769; ABX78769; COXBURSA331_A2125.
KEGGicbs:COXBURSA331_A2125.
PATRICi17928486. VBICoxBur33747_2100.

Phylogenomic databases

eggNOGiCOG0445.
HOGENOMiHOG000201059.
KOiK03495.
OMAiFVEPEGW.
OrthoDBiEOG6W9X6J.

Enzyme and pathway databases

BioCyciCBUR360115:GI0X-2131-MONOMER.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequencing of phylogenetically and phenotypically diverse Coxiella burnetii isolates."
    Seshadri R., Samuel J.E.
    Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 331 / Henzerling II.

Entry informationi

Entry nameiMNMG_COXBR
AccessioniPrimary (citable) accession number: A9NBA8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: July 22, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.