Reviewed, UniProtKB/Swiss-Prot A9NA54 (DCD_COXBR)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	COXBURSA331_A1877

Organism

Coxiella burnetii (strain RSA 331 / Henzerling II) [Complete proteome] [HAMAP]

Taxonomic identifier

360115 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000076617

Sequences

	Sequence		Length	Mass (Da)
	A9NA54-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3AE4A62920DE4C78	FASTA	188	21,135
	10 20 30 40 50 60 MPIKSDKWIR RMAESHQLIY PFEPKQVRET PSGKVISYGT SSYGYDVRCA DEFKIFTNIN 70 80 90 100 110 120 ASIVDPKNFD PNGFIDLKAN VCIIPPNSFV LARTVEYFKI PRNILTICLG KSTYARCGII 130 140 150 160 170 180 VNVTPLEPEW EGHVTLEFSN TTNLPAKIYA NEGVAQMLFL ESDEVCDISY KDRGGKYQGQ KGVTLPVA

References

[1]	"Genome sequencing of phylogenetically and phenotypically diverse Coxiella burnetii isolates." Seshadri R., Samuel J.E. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000890 Genomic DNA. Translation: ABX78754.1.
RefSeq	YP_001597513.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5793047.
GenomeReviews	Gene locus dcd in contig CP000890_GR.
KEGG	cbs:COXBURSA331_A1877.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A9NA54. CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_COXBR

Accession

Primary (citable) accession number: A9NA54

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	June 16, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)