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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Coxiella burnetii (strain RSA 331 / Henzerling II)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi16 – 161Divalent metal cationUniRule annotation
Metal bindingi17 – 171Divalent metal cationUniRule annotation
Metal bindingi47 – 471Divalent metal cationUniRule annotation
Metal bindingi99 – 991Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCBUR360115:GI0X-1868-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:COXBURSA331_A1863
OrganismiCoxiella burnetii (strain RSA 331 / Henzerling II)
Taxonomic identifieri360115 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2582585'-nucleotidase SurEPRO_1000075024Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA9N9U7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A9N9U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTATPKLR LLLSNDDGVY AKGLAILAKT LADLGEVDVV APDRNRSGAS
60 70 80 90 100
NSLTLNAPLH IKNLENGMIS VEGTPTDCVH LAITGVLPEM PDMVVAGINA
110 120 130 140 150
GPNLGDDVWY SGTVAAAMEG RFLGLPALAV SLGGELFRYY ETAAKVVYQL
160 170 180 190 200
IQRIEKDPLP PSTILNINVP DLPYEELKGF EVTRLGTRHR AEPTIRQIDP
210 220 230 240 250
RGHPIYWVGA AGPEQDSGPG TDFFAMNHHC VSITPLRVDL THYEAFDQLA

SWVKRLEM
Length:258
Mass (Da):28,066
Last modified:February 5, 2008 - v1
Checksum:iC620B037CBF471ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000890 Genomic DNA. Translation: ABX78973.1.
RefSeqiWP_005770587.1. NC_010117.1.

Genome annotation databases

EnsemblBacteriaiABX78973; ABX78973; COXBURSA331_A1863.
KEGGicbs:COXBURSA331_A1863.
PATRICi17927973. VBICoxBur33747_1846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000890 Genomic DNA. Translation: ABX78973.1.
RefSeqiWP_005770587.1. NC_010117.1.

3D structure databases

ProteinModelPortaliA9N9U7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX78973; ABX78973; COXBURSA331_A1863.
KEGGicbs:COXBURSA331_A1863.
PATRICi17927973. VBICoxBur33747_1846.

Phylogenomic databases

HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.

Enzyme and pathway databases

BioCyciCBUR360115:GI0X-1868-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSURE_COXBR
AccessioniPrimary (citable) accession number: A9N9U7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.