A9N5X9 (GLNE_SALPB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate-ammonia-ligase adenylyltransferase
EC=2.7.7.42

Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name=ATase
[Glutamate--ammonia-ligase] adenylyltransferase

Gene names

Name:	glnE
Ordered Locus Names:	SPAB_03996

Organism

Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]

Taxonomic identifier

1016998 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella enterica subsp. enterica serovar Paratyphi B

Protein attributes

Sequence length	947 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Adenylation and deadenylation of glutamate--ammonia ligase By similarity. HAMAP MF_00802
Catalytic activity	ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. HAMAP MF_00802
Sequence similarities	Belongs to the glnE family.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW [glutamate-ammonia-ligase] adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 947	947	Glutamate-ammonia-ligase adenylyltransferase HAMAP MF_00802		PRO_1000083702
Regions
	Region	91 – 302	212	GlnE 1 HAMAP MF_00802
	Region	610 – 831	222	GlnE 2 HAMAP MF_00802

Sequences

	Sequence		Length	Mass (Da)
	A9N5X9 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 8B93CB49F3B2AC9C	FASTA	947	108,025
	10 20 30 40 50 60 MTPLSSPLSQ YWQTVVERLP EGFTETSLSA QAKSVLTFSD FALDSVIAHP EWLAELESAS 70 80 90 100 110 120 PQADEWRHYA GWLQEALAGV CDDASLMREL RFFRRRIMVR IAWAQTLSLV DDETILQQLS 130 140 150 160 170 180 HLAETLIVGA RDWLYAACCR EWGTPCNPQG VPQPLLILGM GKLGGGELNF SSDIDLIFAW 190 200 210 220 230 240 PEHGETRGGR RELDNAQFFT RLGQRLIKAL DQPTMDGFVY RVDMRLRPFG DSGPLVLSFA 250 260 270 280 290 300 ALEDYYQEQG RDWERYAMVK ARLMGDNDDA WSRELRAMLR PFVFRRYIDF SVIQSLRNMK 310 320 330 340 350 360 GMIAREVRRR GLKDNIKLGA GGIREIEFIV QVFQLIRGGR EPSLQSRSLL PTLDAIAALH 370 380 390 400 410 420 LLPENDVAQL RVAYLFLRRL ENLLQSINDE QTQTLPADDL NRARLAWGMK AENWPQLVGE 430 440 450 460 470 480 LTDHMANVRR VFNELIGDDE ADTPQEEERS EPWREVWQDA LQEDDSTPVL AHLADEDRRQ 490 500 510 520 530 540 VLTLIADFRK ELDKRPIGPR GRQVLDQLMP HLLADVCSRE DAAVTLSRIT PLLAGIVTRT 550 560 570 580 590 600 TYLELLSEFP GALKHLIMLC AASPMIASQL ARYPLLLDEL LDPGTLYQPT ATDAYRDELR 610 620 630 640 650 660 QYLLRVPEED EEQQLEALRQ FKQAQLLRIA AADIAGTLPV MKVSDHLTWL AEAMIDAVVQ 670 680 690 700 710 720 QAWTQMVARY GQPAHLDERQ GRGFAVVGYG KLGGWELGYS SDLDLIFLHD CPMDVMTNGE 730 740 750 760 770 780 REIDGRQFYL RLAQRIMHLF STRTSSGILY EVDARLRPSG AAGMLVTSAD AFADYQQHEA 790 800 810 820 830 840 WTWEHQALVR ARVVYGDPQL TSQFDTVRRT IMTTARDGKT LQTEVREMRE KMRAHLGNKH 850 860 870 880 890 900 RDRFDIKADE GGITDIEFIA QYLVLRYAHE KPKLTRWSDN VRILELLAQN GIMDEHEAQA 910 920 930 940 LTVAYTTLRD ELHHLALQEL PGHVAQTCFS KERALVQASW RKWLVAV

References

[1]

The Salmonella enterica serovar Paratyphi B Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1250 / SPB7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000886 Genomic DNA. Translation: ABX69325.1.
RefSeq	YP_001590158.1. NC_010102.1.
3D structure databases
ProteinModelPortal	A9N5X9.
SMR	A9N5X9. Positions 1-437.
ModBase	Search...
Protein-protein interaction databases
STRING	A9N5X9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5778444.
GenomeReviews	Gene locus SPAB_03996 in contig CP000886_GR.
KEGG	spq:SPAB_03996.
PATRIC	18534771. VBISalEnt120821_3225.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG687047.
OMA	VEHRIQM.
ProtClustDB	PRK11072.
Family and domain databases
HAMAP	MF_00802. GlnE. [Tree]
InterPro	IPR023057. GlnE. IPR005190. GlnE_rpt_dom. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
KO	K00982.
Pfam	PF08335. GlnD_UR_UTase. 2 hits. PF03710. GlnE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNE_SALPB

Accession

Primary (citable) accession number: A9N5X9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program