A9N5C9 (GLPB_SALPB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	SPAB_00699

Organism

Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]

Taxonomic identifier

1016998 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella enterica subsp. enterica serovar Paratyphi B

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753
Subunit structure	Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycerol catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 419	419	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753		PRO_1000083503

Sequences

	Sequence		Length	Mass (Da)
	A9N5C9 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 50BF55F3EE6461BC	FASTA	419	45,705
	10 20 30 40 50 60 MKFDTVIMGG GLAGLLCGLQ LQQHGLRCAI VTRGQSALHF SSGSLDLLSA LPDGQPVTDI 70 80 90 100 110 120 TAGLDALRRQ APEHPYSRLG AQKVLTLAQQ AQTLLNASGA QLYGDVQQAH QRVTPLGTLR 130 140 150 160 170 180 STWLSSPEVP VWPLSAQRIC VVGVSGLLDF QAHLAAASLR QRDLNVETAE IDLPELDVLR 190 200 210 220 230 240 DNPTEFRAVN IARLLDNEEK WPLLYDALSP IATNCDMIIM PACFGLANDT LWRWLNERLP 250 260 270 280 290 300 CALTLLPTLP PSVLGIRLHN QLQRQFVRQG GIWMPGDEVK KVTCRHGTVS EIWTRNHADI 310 320 330 340 350 360 PLRPRFAVLA SGSFFSSGLV AEREGIREPI LGLDVQQTAT RAEWYQQHFF DPQPWQQFGV 370 380 390 400 410 VTDDAFRPSL AGNTVENLYA IGSVLAGFDP IAEGCGGGVC AVSALQAAHH IAERAGEQQ

References

[1]

The Salmonella enterica serovar Paratyphi B Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1250 / SPB7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000886 Genomic DNA. Translation: ABX66125.1.
RefSeq	YP_001586958.1. NC_010102.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	272994.SPAB_00699.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABX66125; ABX66125; SPAB_00699.
GeneID	5781753.
KEGG	spq:SPAB_00699.
PATRIC	18529397. VBISalEnt120821_0584.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HOG000278489.
KO	K00112.
OMA	FRSVNIS.
ProtClustDB	PRK05329.
Enzyme and pathway databases
BioCyc	SENT28901:GH9O-697-MONOMER.
UniPathway	UPA00618; UER00673.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB.
InterPro	IPR003953. FAD_bind_dom. IPR009158. G3P_DH_GlpB_su. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_SALPB

Accession

Primary (citable) accession number: A9N5C9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program