A9N514 (ULAF_SALPB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
L-ribulose-5-phosphate 4-epimerase UlaF
EC=5.1.3.4

Alternative name(s):
L-ascorbate utilization protein F
Phosphoribulose isomerase

Gene names

Name:	ulaF
Ordered Locus Names:	SPAB_05522

Organism

Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]

Taxonomic identifier

1016998 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella enterica subsp. enterica serovar Paratyphi B

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization By similarity. HAMAP-Rule MF_01952
Catalytic activity	L-ribulose 5-phosphate = D-xylulose 5-phosphate. HAMAP-Rule MF_01952
Cofactor	Binds 1 zinc ion per subunit Potential.
Pathway	Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 4/4. HAMAP-Rule MF_01952
Induction	Induced by L-ascorbate. Repressed by UlaR By similarity. HAMAP-Rule MF_01952
Sequence similarities	Belongs to the aldolase class II family. AraD/FucA subfamily.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	L-ascorbic acid catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	L-ribulose-phosphate 4-epimerase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	L-ribulose-5-phosphate 4-epimerase UlaF HAMAP-Rule MF_01952		PRO_1000088486
Sites
	Metal binding	74	1	Zinc By similarity
	Metal binding	93	1	Zinc By similarity
	Metal binding	95	1	Zinc By similarity
	Metal binding	167	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9N514 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 16399B00A84E55A8	FASTA	228	25,327
	10 20 30 40 50 60 MQKLKQQVFD ANMDLPRYGL VTFTWGNVSA IDRERGLVVI KPSGVAYETM KVDDMVVVDM 70 80 90 100 110 120 DGKVVEGRYR PSSDTATHLA LYQRYPSLGG VVHTHSTHAT AWAQAGMAIP ALGTTHADYF 130 140 150 160 170 180 FGDIPCTRAL SEEEVQGEYE LNTGKVIIET LGEVEPLHTP GIVVYQHGPF AWGKDAHDAV 190 200 210 220 HNAVVMEEVA RMAWIARGIN PALNPIDDYL MNKHFMRKHG PNAYYGQK

References

[1]

The Salmonella enterica serovar Paratyphi B Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1250 / SPB7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000886 Genomic DNA. Translation: ABX70791.1.
RefSeq	YP_001591624.1. NC_010102.1.
3D structure databases
ProteinModelPortal	A9N514.
SMR	A9N514. Positions 1-219.
ModBase	Search...
Protein-protein interaction databases
STRING	272994.SPAB_05522.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABX70791; ABX70791; SPAB_05522.
GeneID	5779130.
KEGG	spq:SPAB_05522.
PATRIC	18537339. VBISalEnt120821_4465.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0235.
HOGENOM	HOG000218183.
KO	K03077.
OMA	KDAHEAV.
ProtClustDB	PRK12348.
Enzyme and pathway databases
BioCyc	SENT28901:GH9O-5509-MONOMER.
UniPathway	UPA00263; UER00380.
Family and domain databases
Gene3D	3.40.225.10. 1 hit.
HAMAP	MF_01952. UlaF.
InterPro	IPR001303. Aldolase_II/adducin_N. IPR023499. UlaF. [Graphical view]
Pfam	PF00596. Aldolase_II. 1 hit. [Graphical view]
SMART	SM01007. Aldolase_II. 1 hit. [Graphical view]
SUPFAM	SSF53639. Aldolase_II_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ULAF_SALPB

Accession

Primary (citable) accession number: A9N514

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program