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A9N4M6 (NAGK_SALPB) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-D-glucosamine kinase

EC=2.7.1.59
Alternative name(s):
GlcNAc kinase
Gene names
Name:nagK
Ordered Locus Names:SPAB_02298
OrganismSalmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]
Taxonomic identifier1016998 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P By similarity. HAMAP-Rule MF_01271

Catalytic activity

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. HAMAP-Rule MF_01271

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01271

Sequence similarities

Belongs to the ROK (NagC/XylR) family. NagK subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303N-acetyl-D-glucosamine kinase HAMAP-Rule MF_01271
PRO_1000085843

Regions

Nucleotide binding4 – 118ATP Potential
Nucleotide binding133 – 1408ATP Potential

Sites

Metal binding1571Zinc By similarity
Metal binding1771Zinc By similarity
Metal binding1791Zinc By similarity
Metal binding1841Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A9N4M6 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 3C3F52B1A63F5468

FASTA30332,992
        10         20         30         40         50         60 
MYYGFDIGGT KIALGVFDST RRLQWEKRVP TPHTSYSAFL DAVCELVAEA DQRFGVKGSV 

        70         80         90        100        110        120 
GIGIPGMPET EDGTLYAANV PAASGKPLRA DLSARLDRDV RLDNDANCFA LSEAWDDEFT 

       130        140        150        160        170        180 
QYPLVMGLIL GTGVGGGLVL NGKPITGQSY ITGEFGHMRL PVDALTLMGF DFPLRRCGCG 

       190        200        210        220        230        240 
QMGCIENYLS GRGFAWLYQH YYDQSLQAPE IIALWEQGDE QAQAHVERYL NLLAVCLGNI 

       250        260        270        280        290        300 
LTIVDPDLLV IGGGLSNFTA ITTQLAERLP RHLLPVARAP RIERARHGDA GGMRGAAFLH 


LTD 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000886 Genomic DNA. Translation: ABX67681.1.
RefSeqYP_001588514.1. NC_010102.1.

3D structure databases

ProteinModelPortalA9N4M6.
SMRA9N4M6. Positions 1-303.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272994.SPAB_02298.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX67681; ABX67681; SPAB_02298.
PATRIC18531984. VBISalEnt120821_1863.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1940.
HOGENOMHOG000150087.
OMAWIGNDAD.
OrthoDBEOG61P6P0.
ProtClustDBPRK13310.

Enzyme and pathway databases

BioCycSENT28901:GH9O-2295-MONOMER.
UniPathwayUPA00544.

Family and domain databases

HAMAPMF_01271. GlcNAc_kinase.
InterProIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
PROSITEPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGK_SALPB
AccessionPrimary (citable) accession number: A9N4M6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: April 16, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways