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Protein

N-acetyl-D-glucosamine kinase

Gene

nagK

Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.UniRule annotation

Catalytic activityi

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.UniRule annotation

Pathwayi: peptidoglycan recycling

This protein is involved in the pathway peptidoglycan recycling, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan recycling and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi157ZincUniRule annotation1
Metal bindingi177ZincUniRule annotation1
Metal bindingi179ZincUniRule annotation1
Metal bindingi184ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi4 – 11ATPUniRule annotation8
Nucleotide bindingi133 – 140ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciSENT1016998:G1GAK-1975-MONOMER
UniPathwayiUPA00544

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetyl-D-glucosamine kinaseUniRule annotation (EC:2.7.1.59UniRule annotation)
Alternative name(s):
GlcNAc kinaseUniRule annotation
Gene namesi
Name:nagKUniRule annotation
Ordered Locus Names:SPAB_02298
OrganismiSalmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Taxonomic identifieri1016998 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000858431 – 303N-acetyl-D-glucosamine kinaseAdd BLAST303

Proteomic databases

PRIDEiA9N4M6

Structurei

3D structure databases

ProteinModelPortaliA9N4M6
SMRiA9N4M6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ROK (NagC/XylR) family. NagK subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000150087
KOiK00884
OMAiLQLNYHA

Family and domain databases

HAMAPiMF_01271 GlcNAc_kinase, 1 hit
InterProiView protein in InterPro
IPR023505 N-acetyl-D-glucosamine_kinase
IPR000600 ROK
PANTHERiPTHR18964 PTHR18964, 1 hit
PfamiView protein in Pfam
PF00480 ROK, 1 hit
PROSITEiView protein in PROSITE
PS01125 ROK, 1 hit

Sequencei

Sequence statusi: Complete.

A9N4M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYYGFDIGGT KIALGVFDST RRLQWEKRVP TPHTSYSAFL DAVCELVAEA
60 70 80 90 100
DQRFGVKGSV GIGIPGMPET EDGTLYAANV PAASGKPLRA DLSARLDRDV
110 120 130 140 150
RLDNDANCFA LSEAWDDEFT QYPLVMGLIL GTGVGGGLVL NGKPITGQSY
160 170 180 190 200
ITGEFGHMRL PVDALTLMGF DFPLRRCGCG QMGCIENYLS GRGFAWLYQH
210 220 230 240 250
YYDQSLQAPE IIALWEQGDE QAQAHVERYL NLLAVCLGNI LTIVDPDLLV
260 270 280 290 300
IGGGLSNFTA ITTQLAERLP RHLLPVARAP RIERARHGDA GGMRGAAFLH

LTD
Length:303
Mass (Da):32,992
Last modified:February 5, 2008 - v1
Checksum:i3C3F52B1A63F5468
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000886 Genomic DNA Translation: ABX67681.1
RefSeqiWP_000291332.1, NC_010102.1

Genome annotation databases

EnsemblBacteriaiABX67681; ABX67681; SPAB_02298
KEGGispq:SPAB_02298
PATRICifig|1016998.12.peg.2173

Similar proteinsi

Entry informationi

Entry nameiNAGK_SALPB
AccessioniPrimary (citable) accession number: A9N4M6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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