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A9MVI4 (MTLD_SALPB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:SPAB_04579
OrganismSalmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]
Taxonomic identifier1016998 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella enterica subsp. enterica serovar Paratyphi B

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000077683

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A9MVI4 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: C5781FBF88C507E1

FASTA38240,900
        10         20         30         40         50         60 
MKALHFGAGN IGRGFIGKLL ADAGIQLTFA DVNQVVLDAL NARHSYQVHV VGENEQVDTV 

        70         80         90        100        110        120 
SGVNAVSSIG DDVVDLIAHV DLITTAVGPV VLERIAPAIA KGLVKRKAQG VDAPLNIIAC 

       130        140        150        160        170        180 
ENMVRGTTQL KGHVMNALAD GDKAWVEQHV GFVDSAVDRI VPPSASATND PLEVTVETFS 

       190        200        210        220        230        240 
EWIVDKTQFK GALPNIPGME LTDNLMAFVE RKLFTLNTGH AITAYLGKLA GHQTIRDAIL 

       250        260        270        280        290        300 
DESIRAVVKG AMEESGAVLI KRYGFDADKH AAYIQKILGR FENPYLKDDV ERVGRQPLRK 

       310        320        330        340        350        360 
LSAGDRLIKP LLGTLEYGLP HVNLVKGIAA AMHFRSDEDP QAQELAALIT EKGPQAALAQ 

       370        380 
ISGLDANSDV VAEAVNAYNA TK

« Hide

References

[1]The Salmonella enterica serovar Paratyphi B Genome Sequencing Project
McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1250 / SPB7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000886 Genomic DNA. Translation: ABX69892.1.
RefSeqYP_001590725.1. NC_010102.1.

3D structure databases

ProteinModelPortalA9MVI4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9MVI4.

Proteomic databases

PRIDEA9MVI4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5779738.
GenomeReviewsGene locus SPAB_04579 in contig CP000886_GR.
KEGGspq:SPAB_04579.
PATRIC18535756. VBISalEnt120821_3707.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_SALPB
AccessionPrimary (citable) accession number: A9MVI4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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