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A9MUV0 (XYLA_SALPB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:SPAB_04547
OrganismSalmonella paratyphi B (strain ATCC BAA-1250 / SPB7) [Complete proteome] [HAMAP]
Taxonomic identifier1016998 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP-Rule MF_00455
PRO_1000081033

Sites

Active site1011 By similarity
Active site1041 By similarity
Metal binding2321Magnesium 1 By similarity
Metal binding2681Magnesium 1 By similarity
Metal binding2681Magnesium 2 By similarity
Metal binding2711Magnesium 2 By similarity
Metal binding2961Magnesium 1 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3091Magnesium 2 By similarity
Metal binding3391Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
A9MUV0 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: E05918AE739D98A7

FASTA44049,667
        10         20         30         40         50         60 
MQAYFDQLDR VRYEGPQSTN PLAFRHYNPD ELVLGKRMED HLRFAACYWH TFCWNGADMF 

        70         80         90        100        110        120 
GVGAFNRPWQ QPGEALELAK RKADVAFEFL HKLNVPFYCF HDVDVSPEGA SLKEYKNNFA 

       130        140        150        160        170        180 
QMVDVLAAKQ EQSGVKLLWG TANCFTNPRY GAGAATNPDP EVFSWAATQV VTAMNATHKL 

       190        200        210        220        230        240 
GGENYVLWGG REGYETLLNT DLRQEREQIG RFMQMVVEHK HKMGFQGTLL IEPKPQEPTK 

       250        260        270        280        290        300 
HQYDYDVATV YGFLKQFGLE KEIKVNIEAN HATLAGHSFH HEIATAIALG IFGSVDANRG 

       310        320        330        340        350        360 
DAQLGWDTDQ FPISVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY DLFYGHIGAM 

       370        380        390        400        410        420 
DTMALSLKIA ARMVEDGELD KRVAKRYAGW NGELGQQILK GQLSLGELAQ YAEQHNLAPV 

       430        440 
HQSGHQELLE NLVNRYLFDK

« Hide

References

[1]The Salmonella enterica serovar Paratyphi B Genome Sequencing Project
McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1250 / SPB7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000886 Genomic DNA. Translation: ABX69860.1.
RefSeqYP_001590693.1. NC_010102.1.

3D structure databases

ProteinModelPortalA9MUV0.
SMRA9MUV0. Positions 3-439.
ModBaseSearch...

Protein-protein interaction databases

STRING272994.SPAB_04547.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX69860; ABX69860; SPAB_04547.
GeneID5779706.
KEGGspq:SPAB_04547.
PATRIC18535702. VBISalEnt120821_3680.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMAHTFQHEL.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycSENT28901:GH9O-4536-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_SALPB
AccessionPrimary (citable) accession number: A9MUV0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: May 29, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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