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Protein

Uronate isomerase

Gene

uxaC

Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SARI_04489
OrganismiSalmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Taxonomic identifieri41514 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002084 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000829651 – 470Uronate isomeraseAdd BLAST470

Proteomic databases

PRIDEiA9MQL9.

Interactioni

Protein-protein interaction databases

STRINGi882884.SARI_04489.

Structurei

3D structure databases

ProteinModelPortaliA9MQL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A9MQL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTFMTKDFL LKNDIARTLY HKYAAPMPIY DFHCHLSPQE IADDRRFDNL
60 70 80 90 100
GQIWLEGDHY KWRALRSAGV DESLITGKET SDYEKYMAWA NTVPKTLGNP
110 120 130 140 150
LYHWTHLELR RPFGITDTLF GPDTAESIWT QCNEKLATPA FSARGIMQQM
160 170 180 190 200
NVRMVGTTDD PIDSLAYHRQ IAADDSFGIE VAPSWRPDKA FKIELDGFVD
210 220 230 240 250
YLGKLEAAAD VNITRFDDLR RALTRRLDHF AACGCRAADH GIETLRFAPV
260 270 280 290 300
PDDAQLDAIL GKRLAGETLS ELEIAQFTTA VLVWLGRQYA ARGWVMQLHI
310 320 330 340 350
GAIRNNNTRM FRLLGPDTGF DSIGDNNISW ALSRLLDSMD VTNELPKTIL
360 370 380 390 400
YCLNPRDNEV LATMTGNFQG PGIAGKVQFG SGWWFNDQKD GMLRQLEQLS
410 420 430 440 450
QMGLLSQFVG MLTDSRSFLS YTRHEYFRRI LCNLLGQWAQ DGEIPDDEAM
460 470
LSRMVQDICF NNAQHYFAIK
Length:470
Mass (Da):53,466
Last modified:February 5, 2008 - v1
Checksum:i26EFC1F2C0CCE7D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000880 Genomic DNA. Translation: ABX24263.1.
RefSeqiWP_000206575.1. NC_010067.1.

Genome annotation databases

EnsemblBacteriaiABX24263; ABX24263; SARI_04489.
KEGGises:SARI_04489.
PATRICi18477922. VBISalEnt13497_4261.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000880 Genomic DNA. Translation: ABX24263.1.
RefSeqiWP_000206575.1. NC_010067.1.

3D structure databases

ProteinModelPortaliA9MQL9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi882884.SARI_04489.

Proteomic databases

PRIDEiA9MQL9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX24263; ABX24263; SARI_04489.
KEGGises:SARI_04489.
PATRICi18477922. VBISalEnt13497_4261.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_SALAR
AccessioniPrimary (citable) accession number: A9MQL9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: November 2, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.