Reviewed, UniProtKB/Swiss-Prot A9MPW2 (GLNE_SALAR)

Names and origin

Protein names

Recommended name:
    Glutamate-ammonia-ligase adenylyltransferase
    EC=2.7.7.42
Alternative name(s):
    [Glutamate--ammonia-ligase] adenylyltransferase
    Glutamine-synthetase adenylyltransferase
      Short name=ATase

Gene names

Name:	glnE
Ordered Locus Names:	SARI_04428

Organism

Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP]

Taxonomic identifier

41514 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	947 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Adenylation and deadenylation of glutamine synthetase By similarity.
Catalytic activity	ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. HAMAP MF_00802
Sequence similarities	Belongs to the glnE family.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW [glutamate-ammonia-ligase] adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 947	947	Glutamate-ammonia-ligase adenylyltransferase HAMAP MF_00802		PRO_1000083701
Regions
	Region	91 – 302	212	GlnE 1 HAMAP MF_00802
	Region	610 – 831	222	GlnE 2 HAMAP MF_00802

Sequences

	Sequence		Length	Mass (Da)
	A9MPW2-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 6C4402EBC28481D7	FASTA	947	108,157
	10 20 30 40 50 60 MTPLSSPLRQ YWQTVVERLP EGFTETSLSA QAKSVLTFSD FALDSVIAHP EWLAELESAS 70 80 90 100 110 120 PQADEWRHYA GWLQEALADV CDDASLMREL RLFRRRIMVR IAWAQALSRV EDETILQQLS 130 140 150 160 170 180 HLAETLIVGA RDWLYAACCR EWGTPCNPQG VPQPLLILGM GKLGGGELNF SSDIDLIFAW 190 200 210 220 230 240 PEHGTTQGGR RELDNAQFFT RLGQRLIKAL DQPTMDGFVY RVDMRLRPFG DSGPLVLSFA 250 260 270 280 290 300 ALEDYYQEQG RDWERYAMVK ARIMGDNNDA WSRELRAMLR PFVFRRYIDF SVIQSLRNMK 310 320 330 340 350 360 GMIAREVRRR GLKDNIKLGA GGIREIEFIV QVFQLIRGGR EPSLQSRSLL PTLNAITALH 370 380 390 400 410 420 LLPENDVTQL RAAYLFLRRL ENLLQSINDE QTQTLPADDL NRARLAWGMN TDNWPQLVGK 430 440 450 460 470 480 LTEHMANVRR VFNELIGDDE ADTPQEEELS EPWREVWQDT LQEGDSTPVL AHLADEDRRQ 490 500 510 520 530 540 LLTLIADFRK ELDKRPIGPR GRQVLDQLMP RLLDDVCSRE DAAVTLSRIT PLLAGIVTRT 550 560 570 580 590 600 TYLELLSEFP GALKHLIMLC AASPMIASQL ARYPLLLDEL LDPGTLYQPT ATNAYRDELR 610 620 630 640 650 660 QYLLRVPEED EEQQLEALRQ FKQAQLLRIA AADIAGTLSV MKVSDHLTWL AEAMIDAVVQ 670 680 690 700 710 720 QAWMQMVARY GQPTHLDERQ GRGFAVVGYG KLGGWELGYS SDLDLIFLHD CPIDVMTNGE 730 740 750 760 770 780 REIDGRQFYL RLAQRIMHLF STRTSSGILY EVDARLRPSG AAGMLVTSAD AFADYQQHEA 790 800 810 820 830 840 WTWEHQALVR ARVVYGDPQL TSQFDAVRRT IMTTARDGKT LQTEVREMRE KMRSHLGNKH 850 860 870 880 890 900 RDRFDIKADE GGITDIEFIA QYLVLRYAHE KPKLTRWSDN VRILELLAQN GIMDEHEAQA 910 920 930 940 LTVAYTTLRD ELHHLALQEL PGHVAQTCFS KERALVQASW RKWLVAV

References

[1]	McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000880 Genomic DNA. Translation: ABX24205.1.
RefSeq	YP_001573347.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5763119.
GenomeReviews	Gene locus SARI_04428 in contig CP000880_GR.
KEGG	ses:SARI_04428.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A9MPW2. WERYAMI.
Family and domain databases
HAMAP	MF_00802. [Tree]
InterPro	IPR005190. GlnE. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF03710. GlnE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNE_SALAR

Accession

Primary (citable) accession number: A9MPW2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)