A9MIH3 (GLK_SALAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	SARI_00481

Organism

Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP]

Taxonomic identifier

41514 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524
Subcellular location	Cytoplasm By similarity HAMAP MF_00524.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glucokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 321	321	Glucokinase HAMAP MF_00524		PRO_1000081697
Regions
	Nucleotide binding	8 – 13	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	A9MIH3 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: EA9D88873CCA23FC	FASTA	321	34,549
	10 20 30 40 50 60 MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVVRVYLD EHSVSVEDGC 70 80 90 100 110 120 IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND FTAVSMAIPM LKKEHLIQFG 130 140 150 160 170 180 GGEPVDGKPI AVYGAGTGLG VAHLVHVDKR WISLPGEGGH VDFAPNSEEE AMILEILRAE 190 200 210 220 230 240 IGHVSAERVL SGPGLVNLYR AIVKSDNRLP ENLRPKDITA RALADSCIDC RRALSLFCVI 250 260 270 280 290 300 MGRFGGDLAL TLGTFGGVYI AGGIVPRFLE FFKASGFRGG FEDKGRFKDY VHSIPVYLIV 310 320 HDNPGLLGSG AHLRQTLGHI L

References

[1]

The Salmonella enterica serovar Arizonae Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-731 / CDC346-86 / RSK2980.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000880 Genomic DNA. Translation: ABX20410.1.
RefSeq	YP_001569552.1. NC_010067.1.
3D structure databases
ProteinModelPortal	A9MIH3.
SMR	A9MIH3. Positions 2-321.
ModBase	Search...
Protein-protein interaction databases
STRING	A9MIH3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5762800.
GenomeReviews	Gene locus SARI_00481 in contig CP000880_GR.
KEGG	ses:SARI_00481.
PATRIC	18470119. VBISalEnt13497_0451.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644410.
OMA	FADKGCM.
ProtClustDB	PRK00292.
Family and domain databases
HAMAP	MF_00524. Glucokinase. [Tree]
InterPro	IPR003836. Glucokinase. [Graphical view]
KO	K00845.
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. Glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_SALAR

Accession

Primary (citable) accession number: A9MIH3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program