Reviewed, UniProtKB/Swiss-Prot A9MI48 (CDH_SALAR)

Names and origin

Protein names

Recommended name:
    CDP-diacylglycerol pyrophosphatase
    EC=3.6.1.26
Alternative name(s):
    CDP-diacylglycerol phosphatidylhydrolase
    CDP-diglyceride hydrolase

Gene names

Name:	cdh
Ordered Locus Names:	SARI_03579

Organism

Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP]

Taxonomic identifier

41514 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	CDP-diacylglycerol + H2O = CMP + phosphatidate. HAMAP MF_00319
Pathway	Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. HAMAP MF_00319
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the cdh family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	CDP-diacylglycerol diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	CDP-diacylglycerol pyrophosphatase HAMAP MF_00319		PRO_1000079161
Regions
	Transmembrane	5 – 25	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	A9MI48-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 36DAA4BC9BBF851B	FASTA	249	28,217
	10 20 30 40 50 60 MKKTGYFLLA VIVIVAAAGV GYWKFSGNPD ALREIVLEQC LPDQLQHQNP APCAEVKPRA 70 80 90 100 110 120 GYVVFKDRHG PLQYLLMPTY RINGTESPLL LEPATPNFFW LAWQARDYMS KKYGHDIPDS 130 140 150 160 170 180 AVSLTVNSRL GRSQDHLHIH ISCIRPDVRE QLDNDLTRIS TRWLPLPGGL MGHEYLARRV 190 200 210 220 230 240 TESELAQRSP FMMLAEEVPE ARDHMGRYGL AVVRQSDGSF VLLATQRNLL TLNRASAEEI QDHQCDILK

References

[1]	McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000880 Genomic DNA. Translation: ABX23394.1.
RefSeq	YP_001572536.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5764296.
GenomeReviews	Gene locus SARI_03579 in contig CP000880_GR.
KEGG	ses:SARI_03579.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A9MI48. EIQDHEC.
Family and domain databases
HAMAP	MF_00319. [Tree]
InterPro	IPR003763. CDP-diacylglyc_Pase_bac. IPR015993. CDP-diacylglyc_Pase_proteobac. [Graphical view]
Pfam	PF02611. CDH. 1 hit. [Graphical view]
PIRSF	PIRSF001273. CDH. 1 hit.
TIGRFAMs	TIGR00672. cdh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CDH_SALAR

Accession

Primary (citable) accession number: A9MI48

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	June 16, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)