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A9MHU8 (PNCB_SALAR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:SARI_01957
OrganismSalmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP]
Taxonomic identifier41514 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000082327

Sequences

Sequence LengthMass (Da)Tools
A9MHU8 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 088098AB83FE4CAE

FASTA40045,841
        10         20         30         40         50         60 
MTQFASPVLH SLLDTDAYKL HMQQAVFHHY YDVQVAAEFR CRGDDLLGIY ADAIREQVDA 

        70         80         90        100        110        120 
MQHLRLQEDE FQWLSGLPFF KTDYLDWLRE FRYDPAQVCV TNDNGKLNIR LTGPWREVIM 

       130        140        150        160        170        180 
WEVPLLAVIS ELVHHYRSPK AGVDQALDAL ESKLVDFTAL TADLDMSRFH LMDFGTRRRF 

       190        200        210        220        230        240 
SREVQQTIVK RLQQEPWFVG TSNYDLARRL ALMPMGTQAH EWFQAHQQIS PDLATSQRAA 

       250        260        270        280        290        300 
LAAWLNEYPD QLGIALTDCI TMDAFLRDFG VEFASHYQGL RHDSGDPVEW GEKAIAHYEK 

       310        320        330        340        350        360 
LGIDPMTKTL VFSDNLDLQK AVELYRHFAS RVQLSFGIGT RLTCDIPQVK PLNIVIKLVE 

       370        380        390        400 
CNGKPVAKLS DSPGKTICHD KAFVRALRKA FDLPQVRKAS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000880 Genomic DNA. Translation: ABX21838.1.

3D structure databases

ProteinModelPortalA9MHU8.
SMRA9MHU8. Positions 2-377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING41514.SARI_01957.

Proteomic databases

PRIDEA9MHU8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX21838; ABX21838; SARI_01957.
PATRIC18473018. VBISalEnt13497_1880.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycSENT882884:GJ8H-1954-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_SALAR
AccessionPrimary (citable) accession number: A9MHU8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways