A9MGI9 (PHNN_SALAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnN
EC=2.7.4.23

Alternative name(s):
Ribose 1,5-bisphosphokinase

Gene names

Name:	phnN
Ordered Locus Names:	SARI_03381

Organism

Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP]

Taxonomic identifier

41514 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica subsp. arizonae

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) By similarity. HAMAP-Rule MF_00836
Catalytic activity	ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00836
Pathway	Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3. HAMAP-Rule MF_00836
Sequence similarities	Belongs to the ribose 1,5-bisphosphokinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	5-phosphoribose 1-diphosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP organic phosphonate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribose 1,5-bisphosphate phosphokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 184	184	Ribose 1,5-bisphosphate phosphokinase PhnN HAMAP-Rule MF_00836		PRO_0000412799
Regions
	Nucleotide binding	9 – 16	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9MGI9 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 04E09AB32FDB7DB5	FASTA	184	20,708
	10 20 30 40 50 60 MGKLIWLMGP SGSGKDSLLA ELRQQEHEQL LIAHRYITRA ANAGNENHIA LSQQEFFIRA 70 80 90 100 110 120 KQNLLALSWY ANGFYYGLGI EIDLWLHAGF DVVVNGSRAH LSQAQARYGT SLLPVCLTVS 130 140 150 160 170 180 PDILRQRLQT RGRENDAEIA ARLERAAHYP PFNCHTVNND GSLLQSVERL LILMGRKEEH YASL

References

[1]

The Salmonella enterica serovar Arizonae Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-731 / CDC346-86 / RSK2980.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000880 Genomic DNA. Translation: ABX23213.1.
RefSeq	YP_001572355.1. NC_010067.1.
3D structure databases
ProteinModelPortal	A9MGI9.
ModBase	Search...
Protein-protein interaction databases
STRING	41514.SARI_03381.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABX23213; ABX23213; SARI_03381.
GeneID	5761038.
KEGG	ses:SARI_03381.
PATRIC	18475744. VBISalEnt13497_3212.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3709.
HOGENOM	HOG000037637.
KO	K05774.
OMA	KVINVTA.
ProtClustDB	PRK10078.
Enzyme and pathway databases
BioCyc	SENT882884:GJ8H-3377-MONOMER.
UniPathway	UPA00087; UER00175.
Family and domain databases
HAMAP	MF_00836. PhnN.
InterPro	IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR012699. PhnN. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR02322. phosphon_PhnN. 1 hit.
PROSITE	PS50052. GUANYLATE_KINASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHNN_SALAR

Accession

Primary (citable) accession number: A9MGI9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 21, 2011
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program