A9MFF9 (ASTB_SALAR) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 23.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: N-succinylarginine dihydrolase EC=3.5.3.23 | ||||
| Gene names |
| ||||
| Organism | Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 41514 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella |
Protein attributes
| Sequence length | 447 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity. HAMAP MF_01172 |
| Catalytic activity | N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172 |
| Pathway | Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172 |
| Subunit structure | Homodimer By similarity. HAMAP MF_01172 |
| Sequence similarities | Belongs to the succinylarginine dihydrolase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | N-succinylarginine dihydrolase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 447 | 447 | N-succinylarginine dihydrolase HAMAP MF_01172 | PRO_1000085395 | |||||
Regions | |||||||||
| Region | 19 – 28 | 10 | Substrate binding By similarity | ||||||
| Region | 137 – 138 | 2 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Active site | 174 | 1 | By similarity | ||||||
| Active site | 248 | 1 | By similarity | ||||||
| Active site | 365 | 1 | Nucleophile By similarity | ||||||
| Binding site | 110 | 1 | Substrate By similarity | ||||||
| Binding site | 212 | 1 | Substrate By similarity | ||||||
| Binding site | 250 | 1 | Substrate By similarity | ||||||
| Binding site | 359 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | The Salmonella enterica serovar Arizonae Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-731 / CDC346-86 / RSK2980. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000880 Genomic DNA. Translation: ABX21564.1. |
| RefSeq | YP_001570706.1. NC_010067.1. |
3D structure databases | |
| ProteinModelPortal | A9MFF9. |
| SMR | A9MFF9. Positions 3-441. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A9MFF9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 5763415. |
| GenomeReviews | Gene locus SARI_01673 in contig CP000880_GR. |
| KEGG | ses:SARI_01673. |
| PATRIC | 18472439. VBISalEnt13497_1595. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG289862. |
| OMA | HFAHHPA. |
| ProtClustDB | PRK13281. |
Family and domain databases | |
| HAMAP | MF_01172. AstB. [Tree] |
| InterPro | IPR007079. SuccinylArg_d-Hdrlase_AstB. [Graphical view] |
| Gene3D | G3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit. |
| KO | K01484. |
| Pfam | PF04996. AstB. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03241. Arg_catab_astB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ASTB_SALAR | ||||||||
| Accession | Primary (citable) accession number: A9MFF9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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