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A9MCW0 (A9MCW0_BRUC2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def EMBL ABX64197.1
Synonyms:def2 HAMAP MF_00163
Ordered Locus Names:BCAN_B1055
OrganismBrucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]
Taxonomic identifier483179 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1491 By similarity HAMAP MF_00163
Metal binding1061Iron By similarity HAMAP MF_00163
Metal binding1481Iron By similarity HAMAP MF_00163
Metal binding1521Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A9MCW0 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: B6B16E9EDDFD7CCC

FASTA18721,001
        10         20         30         40         50         60 
MTILARPITE KSMSVKPLII LPDPVLRQVS KPVERFDDQL RKFASDMFDT MYDAPGIGLA 

        70         80         90        100        110        120 
AIQVGEPIRM LVIDLAKEGE PKAPHIFVNP TIVQSSDKRS TYEEGCLSIP DYYAEVERPA 

       130        140        150        160        170        180 
TVKVNYFDAD GKPQSMEADG LMATCLQHEI DHLNGVLFID HISKLKRDMV IKKFKKLASQ 


RASKKVL

« Hide

References

[1]"Brucella canis ATCC 23365 whole genome shotgun sequencing project."
Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. expand/collapse author list , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000873 Genomic DNA. Translation: ABX64197.1.
RefSeqYP_001594968.1. NC_010104.1.

3D structure databases

ProteinModelPortalA9MCW0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9MCW0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5787299.
GenomeReviewsGene locus BCAN_B1055 in contig CP000873_GR.
KEGGbcs:BCAN_B1055.
PATRIC17835292. VBIBruCan25663_3260.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG665227.
OMARITKVDE.
ProtClustDBPRK00150.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9MCW0_BRUC2
AccessionPrimary (citable) accession number: A9MCW0
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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