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A9MCU8

- RNPA_BRUC2

UniProt

A9MCU8 - RNPA_BRUC2

Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Brucella canis (strain ATCC 23365 / NCTC 10854)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. tRNA binding Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciBCAN483179:GJ7I-3236-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P proteinUniRule annotation
    Short name:
    RNaseP proteinUniRule annotation
    Alternative name(s):
    Protein C5UniRule annotation
    Gene namesi
    Name:rnpAUniRule annotation
    Ordered Locus Names:BCAN_B1043
    OrganismiBrucella canis (strain ATCC 23365 / NCTC 10854)
    Taxonomic identifieri483179 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000001385: Chromosome II

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 141141Ribonuclease P protein componentPRO_1000078189Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi483179.BCAN_B1043.

    Structurei

    3D structure databases

    ProteinModelPortaliA9MCU8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RnpA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0594.
    HOGENOMiHOG000266302.
    KOiK03536.
    OMAiHPCRIRK.
    OrthoDBiEOG6T4S2H.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    HAMAPiMF_00227. RNase_P.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view]
    PfamiPF00825. Ribonuclease_P. 1 hit.
    [Graphical view]
    ProDomiPD003629. Ribonuclease_P. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR00188. rnpA. 1 hit.
    PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9MCU8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKSKKQILRL RKRAEFLTVR NGEKRRGPLF LMEVRERTEE ESNAAKTGDN    50
    PRVGFTVTKK NGNAVIRNRI RRRLKEAIRC HAGRDMAPST DYVIVAREQA 100
    LNAPFSQLTE ELSRRITAKG ERRSGGKRRT ERPEPGPVNG K 141
    Length:141
    Mass (Da):16,153
    Last modified:February 5, 2008 - v1
    Checksum:iF612FA43596B5EF1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000873 Genomic DNA. Translation: ABX64185.1.
    RefSeqiYP_001594956.1. NC_010104.1.

    Genome annotation databases

    EnsemblBacteriaiABX64185; ABX64185; BCAN_B1043.
    GeneIDi5787277.
    KEGGibcs:BCAN_B1043.
    PATRICi17835266. VBIBruCan25663_3247.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000873 Genomic DNA. Translation: ABX64185.1 .
    RefSeqi YP_001594956.1. NC_010104.1.

    3D structure databases

    ProteinModelPortali A9MCU8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 483179.BCAN_B1043.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX64185 ; ABX64185 ; BCAN_B1043 .
    GeneIDi 5787277.
    KEGGi bcs:BCAN_B1043.
    PATRICi 17835266. VBIBruCan25663_3247.

    Phylogenomic databases

    eggNOGi COG0594.
    HOGENOMi HOG000266302.
    KOi K03536.
    OMAi HPCRIRK.
    OrthoDBi EOG6T4S2H.

    Enzyme and pathway databases

    BioCyci BCAN483179:GJ7I-3236-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    HAMAPi MF_00227. RNase_P.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view ]
    Pfami PF00825. Ribonuclease_P. 1 hit.
    [Graphical view ]
    ProDomi PD003629. Ribonuclease_P. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR00188. rnpA. 1 hit.
    PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23365 / NCTC 10854.

    Entry informationi

    Entry nameiRNPA_BRUC2
    AccessioniPrimary (citable) accession number: A9MCU8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3