A9MBN1 (A9MBN1_BRUC2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA topoisomerase IV, B subunit EMBL ABX63768.1

Gene names

Name:	parE EMBL ABX63768.1
Ordered Locus Names:	BCAN_B0592

Organism

Brucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]

Taxonomic identifier

483179 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000380 SAAS SAAS002288 Nucleotide-binding
Molecular function	Isomerase Topoisomerase RuleBase RU000380 SAAS SAAS002288
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9MBN1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 69DE9D6601CA8A02	FASTA	699	77,307
	10 20 30 40 50 60 MDDSNDLFSR VVNNARERQM ERQTGENTVA QPVVQPAPSA PKPVPAAAKA PPAASGGDDY 70 80 90 100 110 120 NASSIRVLEG LEPVRLRPGM YIGGTDEKAL HHLFAEVIDN SMDEAVAGHA NFIEVTVDKE 130 140 150 160 170 180 GFVTVSDNGR GIPVDEHPQV PGKSTLEVIM TKLHAGGKFD GKAYETSGGL HGVGVSVVNA 190 200 210 220 230 240 LSDVLEVEVA RNRRLYRQCF SRGIPQRGLE ELGEVHNRRG TRVRFHPDPE IFGKNAHFDP 250 260 270 280 290 300 HRLYRMARSK AYLFGGVEIR WNCDPSLLDP KKETPEKAVF HFPGGLKDYL EASLGKEHQV 310 320 330 340 350 360 TREVFAGRTE KQGGHGAVEW AVAWFGGDGF VHSYCNTIPT GDGGTHEAGL RIALTRGLKA 370 380 390 400 410 420 YAELTNNKRA SIITTDDVMV SAAGMLSVFI REPEFVGQTK DKLATVEAQR LVENAIRDPF 430 440 450 460 470 480 DHWLAASPQE ASRLLEWVID RADERLRRRQ EKETVRKSAT RKLRLPGKLA DCTQNAAAGA 490 500 510 520 530 540 ELFIVEGDSA GGSAKQARNR ANQAILPLRG KILNVASAGR EKLTANQQIA DLVQALGCGT 550 560 570 580 590 600 RKNYREDDLR YDRVIVMTDA DVDGAHIASL LITFFYQEMP ELIRNGHLYL AVPPLYRLSQ 610 620 630 640 650 660 GGKTAYARDD AHKEELLRTV FTGRGKIEIG RFKGLGEMRA DQLKETTMDP AKRTLLRVQV 670 680 690 DEEYGDETRN TVDDLMGTKP EARFRFIQDR AAFVEELDI

References

[1]

"Brucella canis ATCC 23365 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000873 Genomic DNA. Translation: ABX63768.1.
RefSeq	YP_001594539.1. NC_010104.1.
3D structure databases
ProteinModelPortal	A9MBN1.
ModBase	Search...
Protein-protein interaction databases
STRING	A9MBN1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5786736.
GenomeReviews	Gene locus BCAN_B0592 in contig CP000873_GR.
KEGG	bcs:BCAN_B0592.
PATRIC	17834380. VBIBruCan25663_2810.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	QARDKEF.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9MBN1_BRUC2

Accession

Primary (citable) accession number: A9MBN1

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)