Skip Header

Contribute Send feedback
Read comments (?) or add your own

A9M974 (A9M974_BRUC2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP MF_01023
Gene names
Name:hisC HAMAP MF_01023 EMBL ABX63021.1
Ordered Locus Names:BCAN_A2032
OrganismBrucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]
Taxonomic identifier483179 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2261N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
A9M974 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 9E925FB17E2D93B9

FASTA36840,344
        10         20         30         40         50         60 
MTDMQKPTRP QPKAGVLDIA AYVPGKEHVE GVAKVYKLSS NETPLGPSPH AREAYRHAGE 

        70         80         90        100        110        120 
KLELYPDGQA LALRQAIAET QGLNISNILC GNGSDELLGL LCQTYLAPGD ETIITEHGFA 

       130        140        150        160        170        180 
VYKIQTLAAG ATPVTVKEKN ERIDVDAILA GVTARTKIVF IANPANPTGT YLPFEEVRRL 

       190        200        210        220        230        240 
HAGLPQHVLL VLDAAYAEYV RRNDYEAGLE LVSSNENVVM TRTFSKIHGL PGLRIGWIYA 

       250        260        270        280        290        300 
PLHIIDAMNR IRGPFNMNSA AIAAGAAAIR DRAHVEKSVT YNEKWLAWLT EEFTRLGLRV 

       310        320        330        340        350        360 
TPSVTNFLLI HFPDDAAHSA DKADEWLSRR GYILRRVGGY GFPNALRMTV GPEEANRGVV 


AALTEFLK

« Hide

References

[1]"Brucella canis ATCC 23365 whole genome shotgun sequencing project."
Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. expand/collapse author list , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000872 Genomic DNA. Translation: ABX63021.1.
RefSeqYP_001593792.1. NC_010103.1.

3D structure databases

ProteinModelPortalA9M974.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9M974.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5783908.
GenomeReviewsGene locus BCAN_A2032 in contig CP000872_GR.
KEGGbcs:BCAN_A2032.
PATRIC17832782. VBIBruCan25663_2019.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMAGFLVYRI.
ProtClustDBPRK02731.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001176. ACC_synthase.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9M974_BRUC2
AccessionPrimary (citable) accession number: A9M974
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info