A9M8Z5 (COXZ_BRUC2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Ordered Locus Names:	BCAN_A0477

Organism

Brucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]

Taxonomic identifier

483179 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155		PRO_1000076812
Regions
	Topological domain	1 – 13	13	Cytoplasmic Potential
	Transmembrane	14 – 36	23	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	37 – 201	165	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	A9M8Z5 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 64ED1CCF119944A6	FASTA	201	22,472
	10 20 30 40 50 60 MTDQGENEKK QRRSNATIAV ACLSFFVCMI GAAYASVPLY RIFCQVTGYG GTTQRVEQYS 70 80 90 100 110 120 DTILDKTIKV RFDANIANGL PWDFKPMQRE VTVRIGETTM IKYEAHNLFG EETYGRASFN 130 140 150 160 170 180 VAPGRAGAYF NKVECFCFTD NTLKPGEDLE LPVVFFVDPE FVNDPDLKDV KTITLSYTFF 190 200 PIDKPRPVVN AKAVGSTRNG G

References

[1]

"Brucella canis ATCC 23365 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23365 / NCTC 10854.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000872 Genomic DNA. Translation: ABX61559.1.
RefSeq	YP_001592330.1. NC_010103.1.
3D structure databases
ProteinModelPortal	A9M8Z5.
SMR	A9M8Z5. Positions 56-181.
ModBase	Search...
Protein-protein interaction databases
STRING	A9M8Z5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5785232.
GenomeReviews	Gene locus BCAN_A0477 in contig CP000872_GR.
KEGG	bcs:BCAN_A0477.
PATRIC	17829630. VBIBruCan25663_0488.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG525908.
OMA	KLIFYRA.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	BCAN483179:BCAN_A0477-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_BRUC2

Accession

Primary (citable) accession number: A9M8Z5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program