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A9M8V2

- AROC_BRUC2

UniProt

A9M8V2 - AROC_BRUC2

Protein

Chorismate synthase

Gene

aroC

Organism
Brucella canis (strain ATCC 23365 / NCTC 10854)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.UniRule annotation

    Cofactori

    Reduced flavin.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. chorismate synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
    2. chorismate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis

    Enzyme and pathway databases

    BioCyciBCAN483179:GJ7I-428-MONOMER.
    UniPathwayiUPA00053; UER00090.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chorismate synthaseUniRule annotation (EC:4.2.3.5UniRule annotation)
    Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyaseUniRule annotation
    Gene namesi
    Name:aroCUniRule annotation
    Ordered Locus Names:BCAN_A0432
    OrganismiBrucella canis (strain ATCC 23365 / NCTC 10854)
    Taxonomic identifieri483179 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000001385: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 364364Chorismate synthasePRO_1000078986Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi483179.BCAN_A0432.

    Structurei

    3D structure databases

    ProteinModelPortaliA9M8V2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chorismate synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0082.
    HOGENOMiHOG000060335.
    KOiK01736.
    OMAiNADEIFM.
    OrthoDBiEOG6WDSHT.

    Family and domain databases

    Gene3Di3.60.150.10. 1 hit.
    HAMAPiMF_00300. Chorismate_synth.
    InterProiIPR000453. Chorismate_synth.
    IPR020541. Chorismate_synthase_CS.
    [Graphical view]
    PANTHERiPTHR21085. PTHR21085. 1 hit.
    PfamiPF01264. Chorismate_synt. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001456. Chorismate_synth. 1 hit.
    SUPFAMiSSF103263. SSF103263. 1 hit.
    TIGRFAMsiTIGR00033. aroC. 1 hit.
    PROSITEiPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
    PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
    PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9M8V2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHNSFGHLF RVTTWGESHG LALGCVVDGC PPGITFTEAE IQSFLDKRKP    50
    GQSKYTTQRR EPDQVRVLSG VLLGEDGVTM TTTGTPISMM IENTDQRSKD 100
    YGEIARQYRP GHADYAYDVK YGIRDYRGGG RSSARETAAR VAAGAIARKV 150
    VPGLEVRGAL VSIGAHDIDR SRWNWAEVDN NPFFTPDAGS VEVFADYLDG 200
    IRKNGSSVGA IIEIVAEGVP AGIGAPIYGK LDQDIASYLM SINAVKGVEI 250
    GNGFEAARLT GEENADEMRM GNDGKPIFLS NHAGGVLGGI ATGAPVVARF 300
    AVKPTSSILT PRRSIDKDGN EVDVMTRGRH DPCVGIRAVP IGEAMVACAI 350
    ADHYLRHRGQ TGRV 364
    Length:364
    Mass (Da):38,988
    Last modified:February 5, 2008 - v1
    Checksum:i95F83B4FD5230C0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000872 Genomic DNA. Translation: ABX61516.1.
    RefSeqiYP_001592287.1. NC_010103.1.

    Genome annotation databases

    EnsemblBacteriaiABX61516; ABX61516; BCAN_A0432.
    GeneIDi5786003.
    KEGGibcs:BCAN_A0432.
    PATRICi17829540. VBIBruCan25663_0443.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000872 Genomic DNA. Translation: ABX61516.1 .
    RefSeqi YP_001592287.1. NC_010103.1.

    3D structure databases

    ProteinModelPortali A9M8V2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 483179.BCAN_A0432.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX61516 ; ABX61516 ; BCAN_A0432 .
    GeneIDi 5786003.
    KEGGi bcs:BCAN_A0432.
    PATRICi 17829540. VBIBruCan25663_0443.

    Phylogenomic databases

    eggNOGi COG0082.
    HOGENOMi HOG000060335.
    KOi K01736.
    OMAi NADEIFM.
    OrthoDBi EOG6WDSHT.

    Enzyme and pathway databases

    UniPathwayi UPA00053 ; UER00090 .
    BioCyci BCAN483179:GJ7I-428-MONOMER.

    Miscellaneous databases

    PROi A9M8V2.

    Family and domain databases

    Gene3Di 3.60.150.10. 1 hit.
    HAMAPi MF_00300. Chorismate_synth.
    InterProi IPR000453. Chorismate_synth.
    IPR020541. Chorismate_synthase_CS.
    [Graphical view ]
    PANTHERi PTHR21085. PTHR21085. 1 hit.
    Pfami PF01264. Chorismate_synt. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001456. Chorismate_synth. 1 hit.
    SUPFAMi SSF103263. SSF103263. 1 hit.
    TIGRFAMsi TIGR00033. aroC. 1 hit.
    PROSITEi PS00787. CHORISMATE_SYNTHASE_1. 1 hit.
    PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
    PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23365 / NCTC 10854.

    Entry informationi

    Entry nameiAROC_BRUC2
    AccessioniPrimary (citable) accession number: A9M8V2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3