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A9M8V2

- AROC_BRUC2

UniProt

A9M8V2 - AROC_BRUC2

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Protein

Chorismate synthase

Gene

aroC

Organism
Brucella canis (strain ATCC 23365 / NCTC 10854)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.UniRule annotation

Cofactori

Reduced flavin.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. chorismate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis

Enzyme and pathway databases

BioCyciBCAN483179:GJ7I-428-MONOMER.
UniPathwayiUPA00053; UER00090.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate synthaseUniRule annotation (EC:4.2.3.5UniRule annotation)
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyaseUniRule annotation
Gene namesi
Name:aroCUniRule annotation
Ordered Locus Names:BCAN_A0432
OrganismiBrucella canis (strain ATCC 23365 / NCTC 10854)
Taxonomic identifieri483179 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000001385: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 364364Chorismate synthasePRO_1000078986Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi483179.BCAN_A0432.

Structurei

3D structure databases

ProteinModelPortaliA9M8V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chorismate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0082.
HOGENOMiHOG000060335.
KOiK01736.
OMAiNADEIFM.
OrthoDBiEOG6WDSHT.

Family and domain databases

Gene3Di3.60.150.10. 1 hit.
HAMAPiMF_00300. Chorismate_synth.
InterProiIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
PANTHERiPTHR21085. PTHR21085. 1 hit.
PfamiPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMiSSF103263. SSF103263. 1 hit.
TIGRFAMsiTIGR00033. aroC. 1 hit.
PROSITEiPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9M8V2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHNSFGHLF RVTTWGESHG LALGCVVDGC PPGITFTEAE IQSFLDKRKP
60 70 80 90 100
GQSKYTTQRR EPDQVRVLSG VLLGEDGVTM TTTGTPISMM IENTDQRSKD
110 120 130 140 150
YGEIARQYRP GHADYAYDVK YGIRDYRGGG RSSARETAAR VAAGAIARKV
160 170 180 190 200
VPGLEVRGAL VSIGAHDIDR SRWNWAEVDN NPFFTPDAGS VEVFADYLDG
210 220 230 240 250
IRKNGSSVGA IIEIVAEGVP AGIGAPIYGK LDQDIASYLM SINAVKGVEI
260 270 280 290 300
GNGFEAARLT GEENADEMRM GNDGKPIFLS NHAGGVLGGI ATGAPVVARF
310 320 330 340 350
AVKPTSSILT PRRSIDKDGN EVDVMTRGRH DPCVGIRAVP IGEAMVACAI
360
ADHYLRHRGQ TGRV
Length:364
Mass (Da):38,988
Last modified:February 5, 2008 - v1
Checksum:i95F83B4FD5230C0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000872 Genomic DNA. Translation: ABX61516.1.
RefSeqiYP_001592287.1. NC_010103.1.

Genome annotation databases

EnsemblBacteriaiABX61516; ABX61516; BCAN_A0432.
GeneIDi5786003.
KEGGibcs:BCAN_A0432.
PATRICi17829540. VBIBruCan25663_0443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000872 Genomic DNA. Translation: ABX61516.1 .
RefSeqi YP_001592287.1. NC_010103.1.

3D structure databases

ProteinModelPortali A9M8V2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 483179.BCAN_A0432.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX61516 ; ABX61516 ; BCAN_A0432 .
GeneIDi 5786003.
KEGGi bcs:BCAN_A0432.
PATRICi 17829540. VBIBruCan25663_0443.

Phylogenomic databases

eggNOGi COG0082.
HOGENOMi HOG000060335.
KOi K01736.
OMAi NADEIFM.
OrthoDBi EOG6WDSHT.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00090 .
BioCyci BCAN483179:GJ7I-428-MONOMER.

Miscellaneous databases

PROi A9M8V2.

Family and domain databases

Gene3Di 3.60.150.10. 1 hit.
HAMAPi MF_00300. Chorismate_synth.
InterProi IPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view ]
PANTHERi PTHR21085. PTHR21085. 1 hit.
Pfami PF01264. Chorismate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001456. Chorismate_synth. 1 hit.
SUPFAMi SSF103263. SSF103263. 1 hit.
TIGRFAMsi TIGR00033. aroC. 1 hit.
PROSITEi PS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23365 / NCTC 10854.

Entry informationi

Entry nameiAROC_BRUC2
AccessioniPrimary (citable) accession number: A9M8V2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: October 1, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3