A9M8M3 (GCP_BRUC2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BCAN_A1931

Organism

Brucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]

Taxonomic identifier

483179 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000087468

Sequences

	Sequence		Length	Mass (Da)
	A9M8M3 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 9F005EAD34760BC4	FASTA	359	37,982
	10 20 30 40 50 60 MRVLGIETSC DETAAAIVQR DDMGEGRILS NVVLSQIAEH EPYGGVVPEI AARAHVEALD 70 80 90 100 110 120 RLVDRALNDA GLKLYEVDAV AATAGPGLIG GLIVGLMTAK ALAMAAQKPF YAVNHLEGHA 130 140 150 160 170 180 LTARLTDGLP FPYLLLLVSG GHTQMVLVRG IGDYERLGTT IDDALGEAFD KTAKLLGLPY 190 200 210 220 230 240 PGGPAVERMA LQGDQKRFAL PRPLKGEARL DFSFSGLKTA VRQTATELVP LTDQDVTDIC 250 260 270 280 290 300 ASFQAAVADT LSDRVGRSLE RFKTEFPDCA TPSLVVAGGV AANKTLRAAL ENLCTRHGFA 310 320 330 340 350 FIAPPLNLCT DNAAMIAWAG AERAATQAPD SLDIAPRSRW PLDEKSAPVF GTGRRGAKA

References

[1]

"Brucella canis ATCC 23365 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23365 / NCTC 10854.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000872 Genomic DNA. Translation: ABX62921.1.
RefSeq	YP_001593692.1. NC_010103.1.
3D structure databases
ProteinModelPortal	A9M8M3.
ModBase	Search...
Protein-protein interaction databases
STRING	A9M8M3.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5785342.
GenomeReviews	Gene locus BCAN_A1931 in contig CP000872_GR.
KEGG	bcs:BCAN_A1931.
PATRIC	17832581. VBIBruCan25663_1920.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BCAN483179:BCAN_A1931-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BRUC2

Accession

Primary (citable) accession number: A9M8M3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program