A9M8A2 (A9M8A2_BRUC2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL ABX61418.1

Gene names

Name:	hemA EMBL ABX61418.1
Ordered Locus Names:	BCAN_A0328

Organism

Brucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]

Taxonomic identifier

483179 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Transferase RuleBase RU003693
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9M8A2 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 8F991D5EAB916A8A	FASTA	425	46,151
	10 20 30 40 50 60 MDYRRFFEEA IDQLHAEKRY RVFADLERIV GRFPQAIWRN NGTAREITVW CSNDYLGMGH 70 80 90 100 110 120 HPDVIKAMCE TAGSAGSGAG GTRNISGNNH PLVELESELA DLHGKEAGLV FTSGFVSNEA 130 140 150 160 170 180 SISTIARLLP NCLILSDELN HASMIEGVRH SGAEKKIFRH NDVEHLEQLL KAADRSRAKL 190 200 210 220 230 240 IVFESVYSMD GDIAPIEKIA DLADKYNAMT YIDEVHAVGM YGAHGGGITE RDGLAHRIDI 250 260 270 280 290 300 IEGTLAKAFG ALGGYITGSR AIIDAVRSYA PGFIFTTSLP PAVAAAATAA IRHLKSSQAE 310 320 330 340 350 360 RDGQQRQAQR AKDVLSAAGL PVMPSQTHIV PILVGDPELC KKASDRLLEV HGIYIQPINY 370 380 390 400 410 420 PTVPRGTERL RITPSPLHDD KLIDGLKDAL LEIWNELGIP FAEPSAPQAA NSDRIIPLMV SKAGG

References

[1]

"Brucella canis ATCC 23365 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000872 Genomic DNA. Translation: ABX61418.1.
RefSeq	YP_001592189.1. NC_010103.1.
3D structure databases
ProteinModelPortal	A9M8A2.
SMR	A9M8A2. Positions 2-394.
ModBase	Search...
Protein-protein interaction databases
STRING	A9M8A2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5785601.
GenomeReviews	Gene locus BCAN_A0328 in contig CP000872_GR.
KEGG	bcs:BCAN_A0328.
PATRIC	17829317. VBIBruCan25663_0332.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649839.
OMA	HLKESNE.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9M8A2_BRUC2

Accession

Primary (citable) accession number: A9M8A2

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)