A9M7T6 (IF1_BRUC2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-1

Gene names

Name:	infA
Ordered Locus Names:	BCAN_A0253

Organism

Brucella canis (strain ATCC 23365 / NCTC 10854) [Complete proteome] [HAMAP]

Taxonomic identifier

483179 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3. HAMAP MF_00075
Subcellular location	Cytoplasm HAMAP MF_00075.
Sequence similarities	Belongs to the IF-1 family. Contains 1 S1-like domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 72	72	Translation initiation factor IF-1 HAMAP MF_00075		PRO_0000338772
Regions
	Domain	1 – 72	72	S1-like

Sequences

	Sequence		Length	Mass (Da)
	A9M7T6 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 67DFD20EB09AE093	FASTA	72	8,338
	10 20 30 40 50 60 MAKEEVLEFP GVVTELLPNA MFRVKLENEH EIIAHTAGRM RKNRIRVLAG DKVLVEMTPY 70 DLTKGRITYR LK

References

[1]

"Brucella canis ATCC 23365 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23365 / NCTC 10854.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000872 Genomic DNA. Translation: ABX61346.1.
RefSeq	YP_001592117.1. NC_010103.1.
3D structure databases
ProteinModelPortal	A9M7T6.
SMR	A9M7T6. Positions 2-70.
ModBase	Search...
Protein-protein interaction databases
STRING	A9M7T6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5785464.
GenomeReviews	Gene locus BCAN_A0253 in contig CP000872_GR.
KEGG	bcs:BCAN_A0253.
PATRIC	17829169. VBIBruCan25663_0260.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG286099.
OMA	VQLDAGH.
ProtClustDB	PRK00276.
Enzyme and pathway databases
BioCyc	BCAN483179:BCAN_A0253-MONOMER.
Family and domain databases
HAMAP	MF_00075. IF-1. [Tree]
InterPro	IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR022967. RNA-binding_domain_S1. IPR006196. RNA-binding_domain_S1_IF1. IPR004368. TIF_IF1. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K02518.
Pfam	PF01176. eIF-1a. 1 hit. [Graphical view]
SMART	SM00316. S1. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00008. InfA. 1 hit.
PROSITE	PS50832. S1_IF1_TYPE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF1_BRUC2

Accession

Primary (citable) accession number: A9M7T6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program