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Protein

NAD(P)H dehydrogenase (quinone)

Gene

BCAN_A1063

Organism
Brucella canis (strain ATCC 23365 / NCTC 10854)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12NAD(P)UniRule annotation1
Binding sitei98SubstrateUniRule annotation1
Binding sitei134FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 14FMNUniRule annotation5
Nucleotide bindingi110 – 162FMNUniRule annotationAdd BLAST53

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD, NADP, Nucleotide-binding

Protein family/group databases

CAZyiAA6. Auxiliary Activities 6.

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:BCAN_A1063
OrganismiBrucella canis (strain ATCC 23365 / NCTC 10854)
Taxonomic identifieri483179 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000001385 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000841301 – 199NAD(P)H dehydrogenase (quinone)Add BLAST199

Structurei

3D structure databases

ProteinModelPortaliA9M560.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 190Flavodoxin-likeUniRule annotationAdd BLAST187

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation
Contains 1 flavodoxin-like domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000030539.
KOiK03809.
OMAiWMKGALV.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_dom.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9M560-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKMLVLYYS AYGHMEQMAK AAAEGAREGG AEVTLKRVPE LVPEEVAKAS
60 70 80 90 100
HYKIDQEAPI ATPGELADYD AIIIGTATRY GMMASQMKNF LDQTGGLWAK
110 120 130 140 150
GALINKVGSV MVSTATQYGG AELALISTQW QMQHHGMIIV PLSYAYREQM
160 170 180 190
GNDVVRGGAP YGMTTTADGD GSRQPSAQEL DGARFQGRRV AEITAKLHG
Length:199
Mass (Da):21,414
Last modified:February 5, 2008 - v1
Checksum:iD3870D2520742744
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000872 Genomic DNA. Translation: ABX62115.1.
RefSeqiWP_004690843.1. NC_010103.1.

Genome annotation databases

EnsemblBacteriaiABX62115; ABX62115; BCAN_A1063.
KEGGibcs:BCAN_A1063.
PATRICi17830823. VBIBruCan25663_1073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000872 Genomic DNA. Translation: ABX62115.1.
RefSeqiWP_004690843.1. NC_010103.1.

3D structure databases

ProteinModelPortaliA9M560.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiAA6. Auxiliary Activities 6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX62115; ABX62115; BCAN_A1063.
KEGGibcs:BCAN_A1063.
PATRICi17830823. VBIBruCan25663_1073.

Phylogenomic databases

HOGENOMiHOG000030539.
KOiK03809.
OMAiWMKGALV.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_dom.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNQOR_BRUC2
AccessioniPrimary (citable) accession number: A9M560
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: November 2, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.