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A9L937 (HXA2_PAPAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Homeobox protein Hox-A2
Gene names
Name:HOXA2
OrganismPapio anubis (Olive baboon)
Taxonomic identifier9555 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family. Proboscipedia subfamily.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 377377Homeobox protein Hox-A2
PRO_0000333802

Regions

DNA binding144 – 20360Homeobox
Motif94 – 996Antp-type hexapeptide

Sequences

Sequence LengthMass (Da)Tools
A9L937 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 5D289A5E10FEAEAB

FASTA37741,162
        10         20         30         40         50         60 
MNYEFEREIG FINSQPSLAE CLTSFPPVAD TFQSSSIKTS TLSHSTLIPP PFEQTIPSLN 

        70         80         90        100        110        120 
PSNHPRHGAG GRPKPSPAGS RGSPVPAGAL QPPEYPWMKE KKAAKKTALP PAAAAAAAAA 

       130        140        150        160        170        180 
AATGPACLSH KESLEIADGS GGGSRRLRTA YTNTQLLELE KEFHFNKYLC RPRRVEIAAL 

       190        200        210        220        230        240 
LDLTERQVKV WFQNRRMKHK RQTQCKENQN SEGKCKSLED SEKVEEEEEE KTLFEQALSV 

       250        260        270        280        290        300 
SGALLEREGY TFQQNALSQQ QAPSGHNGDS QSFPVSPLTS NEKNLKHFQH QSPTVPNCLS 

       310        320        330        340        350        360 
TMGQNCGAGL NNDSPEALEV PSLQDFNVFS TDSCLQLSDT VSPSLPGSLD SPVDISADSF 

       370 
DFFTDTLTTI DLQHLNY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DP000507 Genomic DNA. Translation: ABX52200.1.
RefSeqNP_001162366.1. NM_001168895.1.
UniGenePan.18114.

3D structure databases

ProteinModelPortalA9L937.
SMRA9L937. Positions 144-202.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100137359.

Organism-specific databases

CTD3199.

Phylogenomic databases

HOVERGENHBG006088.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXA2_PAPAN
AccessionPrimary (citable) accession number: A9L937
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries