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A9L8U6

- A9L8U6_PAPAN

UniProt

A9L8U6 - A9L8U6_PAPAN

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Protein
Submitted name:

Axin 1, isoform 1 (Predicted)

Gene

AXIN1

Organism
Papio anubis (Olive baboon)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. signal transducer activity Source: Ensembl

GO - Biological processi

  1. activation of protein kinase activity Source: Ensembl
  2. axial mesoderm formation Source: Ensembl
  3. canonical Wnt signaling pathway Source: Ensembl
  4. cellular protein complex assembly Source: Ensembl
  5. cytoplasmic microtubule organization Source: Ensembl
  6. dorsal/ventral axis specification Source: Ensembl
  7. genetic imprinting Source: Ensembl
  8. in utero embryonic development Source: Ensembl
  9. negative regulation of canonical Wnt signaling pathway Source: Ensembl
  10. negative regulation of fat cell differentiation Source: Ensembl
  11. negative regulation of protein metabolic process Source: Ensembl
  12. negative regulation of transcription elongation from RNA polymerase II promoter Source: Ensembl
  13. nucleocytoplasmic transport Source: Ensembl
  14. positive regulation of JNK cascade Source: Ensembl
  15. positive regulation of JUN kinase activity Source: Ensembl
  16. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  17. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
  18. positive regulation of transcription, DNA-templated Source: Ensembl
  19. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  20. positive regulation of ubiquitin-protein transferase activity Source: Ensembl
  21. post-anal tail morphogenesis Source: Ensembl
  22. protein catabolic process Source: Ensembl
  23. protein homooligomerization Source: Ensembl
  24. protein polyubiquitination Source: Ensembl
  25. regulation of catenin import into nucleus Source: Ensembl
  26. sensory perception of sound Source: Ensembl
  27. termination of G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Axin 1, isoform 1 (Predicted)Imported
Gene namesi
Name:AXIN1Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio

Subcellular locationi

GO - Cellular componenti

  1. beta-catenin destruction complex Source: Ensembl
  2. cell cortex Source: Ensembl
  3. cytoplasmic membrane-bounded vesicle Source: Ensembl
  4. cytoplasmic microtubule Source: Ensembl
  5. lateral plasma membrane Source: Ensembl
  6. nucleus Source: Ensembl
  7. perinuclear region of cytoplasm Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA9L8U6.
SMRiA9L8U6. Positions 74-220, 784-867.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 RGS domain.UniRule annotation

Phylogenomic databases

HOVERGENiHBG004324.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR014936. Axin_b-cat-bd.
IPR001158. DIX.
IPR024066. Regulat_G_prot_signal_dom1.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9L8U6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNIQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPA SYSFCSGKGV
60 70 80 90 100
GIKAETSTAT PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIS
110 120 130 140 150
LFRTFLKQEG CADLLDFWFA CTGFRKLEPC DSNEEKRLKL ARAIYRKYIL
160 170 180 190 200
DNNGIVSRQT KPATKSFIKG CIMKQLIDPA MFDQAQTEIQ ATMEENTYPS
210 220 230 240 250
FLKSDIYLEY TRTGSESPKV CSDQSSGSGT GKGISGYLPT LNEDEEWKCD
260 270 280 290 300
QDMDEDDGRD AAPPGRLPQK LLLETAAPRA SSSRRYSEGR EFRYGSWREP
310 320 330 340 350
VNPYYVNAGY ALAPATSAND SEQQSLSSDA DTLSLTDSSV DGIPPYRIRK
360 370 380 390 400
QHRREMQESV QVNGRVPLPH IPRTYRVPKE VRVEPQKFAE ELIHRLEAVQ
410 420 430 440 450
RTREAEEKLE ERLKRVRMEE EGEDGDPSSG LPGPCHKLPP APAWHHFPPR
460 470 480 490 500
CVDVGCAGLR DAHEENPESI LDEHVQRVLR TPGRQSPGPG HRSPDSGHMA
510 520 530 540 550
KMPVALGSAA SGHGKHAPKS GVKLDAAGLH HHRHVHHHVH HSTARPKEQV
560 570 580 590 600
EAEAARRAQS SFAWGPEPHS HGAKSRGYSE SVGAAPNASD GLAHSGKAGM
610 620 630 640 650
ACKRNAKKAE SGKSASAEVP GASEDAEKNQ KIMQWIIEGE KEISRHRRTG
660 670 680 690 700
HGSSGTRKPQ PHENSRPLSL ERPGAVHPWA GPQLRTSVQP SHLFIQDPTM
710 720 730 740 750
PPHPAPNPLT QLEEARRRLE EEEKRASRAP SKQRYVQEVM RRGRACVRPA
760 770 780 790 800
CAPVLRVVPA VSDMELSETE TRSQRKAGGG SAQPCDSIVV AYYFCGEPIP
810 820 830 840 850
YRTLVRGRAV TLGQFKELLT KKGSYRYYFK KVSDEFDCGV VFEEVREDEA
860
VLPVFEEKII GKVEKVD
Length:867
Mass (Da):96,038
Last modified:February 5, 2008 - v1
Checksum:iBCAF215B73BB1BF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000504 Genomic DNA. Translation: ABX52109.1.
RefSeqiNP_001162523.1. NM_001169052.1.
UniGeneiPan.17958.

Genome annotation databases

GeneIDi100137557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000504 Genomic DNA. Translation: ABX52109.1 .
RefSeqi NP_001162523.1. NM_001169052.1.
UniGenei Pan.17958.

3D structure databases

ProteinModelPortali A9L8U6.
SMRi A9L8U6. Positions 74-220, 784-867.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100137557.

Organism-specific databases

CTDi 8312.

Phylogenomic databases

HOVERGENi HBG004324.

Family and domain databases

Gene3Di 1.10.196.10. 2 hits.
InterProi IPR014936. Axin_b-cat-bd.
IPR001158. DIX.
IPR024066. Regulat_G_prot_signal_dom1.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view ]
PRINTSi PR01301. RGSPROTEIN.
SMARTi SM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view ]
SUPFAMi SSF48097. SSF48097. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA9L8U6_PAPAN
AccessioniPrimary (citable) accession number: A9L8U6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)