ID   A9L5F9_SHEB9            Unreviewed;       803 AA.
AC   A9L5F9;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Adenylate cyclase {ECO:0000256|ARBA:ARBA00021420};
DE            EC=4.6.1.1 {ECO:0000256|ARBA:ARBA00012201};
DE   AltName: Full=ATP pyrophosphate-lyase {ECO:0000256|ARBA:ARBA00032597};
DE   AltName: Full=Adenylyl cyclase {ECO:0000256|ARBA:ARBA00032637};
GN   OrderedLocusNames=Sbal195_4093 {ECO:0000313|EMBL:ABX51253.1};
OS   Shewanella baltica (strain OS195).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=399599 {ECO:0000313|EMBL:ABX51253.1, ECO:0000313|Proteomes:UP000000770};
RN   [1] {ECO:0000313|EMBL:ABX51253.1, ECO:0000313|Proteomes:UP000000770}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OS195 {ECO:0000313|EMBL:ABX51253.1,
RC   ECO:0000313|Proteomes:UP000000770};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Brettar I.,
RA   Rodrigues J., Konstantinidis K., Klappenbach J., Hofle M., Tiedje J.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Shewanella baltica OS195.";
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP = 3',5'-cyclic AMP + diphosphate; Xref=Rhea:RHEA:15389,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58165; EC=4.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001593};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-1 family.
CC       {ECO:0000256|ARBA:ARBA00007901, ECO:0000256|RuleBase:RU004184}.
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DR   EMBL; CP000891; ABX51253.1; -; Genomic_DNA.
DR   RefSeq; WP_012197714.1; NC_009997.1.
DR   AlphaFoldDB; A9L5F9; -.
DR   GeneID; 11774086; -.
DR   KEGG; sbn:Sbal195_4093; -.
DR   HOGENOM; CLU_013280_0_0_6; -.
DR   Proteomes; UP000000770; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024686; Adenylate_cyclase_1_CS.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
DR   PIRSF; PIRSF001444; Adenylate_cycl; 2.
DR   PROSITE; PS01092; ADENYLATE_CYCLASE_1_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   cAMP biosynthesis {ECO:0000256|ARBA:ARBA00022998};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ABX51253.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          10..201
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   803 AA;  92476 MW;  EAF57F987701109C CRC64;
     MDRQIQFPDI AERLNKVRIA RALALLSPLQ KHLFHLIPFL IHQNSVQYPG YHAANTPCGI
     NEYQLSEIES QACDVFSLPF INQEADINAF DGVYAMGSTG SFGQNTKSDV DVWLVHRADL
     SLEELALIRI KTDRLTAWFA EYQFEVNFYL VHPQQFCGDQ TLRGCLSTMA HEHSGSTQHW
     LLLEEFYRSQ IRLAGKAIAW WPDAKLNPAL LFLGDVHELP ASEYFGASLW QLYKGLEKPH
     KALIKVLLLE AYASDYPNST VLCDRLWQKT LAGDFSTSND AYYSIYEIIE TYLFKQNDTR
     RLEIARRCFY LKCGVHLSRT QEGKDWRYPK LQKLVQDWQW PDSLISTLDD CEHWHSGQLN
     WFNEQLNELL LASYQTLLRF ASTHELNEGL RIEELGMLTR KLHTYFSQDE DQIAKLNLLW
     SASVAESDVT MVSSSRERQY YLYRQEPLPQ NLLGESAICK GKTPSALMIW ACLNGISTPE
     TQWHEYGQSK AKSKRLTEAS KRLLNFIDHD WRVSKRDLCQ PWHFRKLIFV LNLDCDPTIE
     WGGQEMMVDV MNANVFSLGR KKANMLGALD AICLNSWGEW QCHRFEGDTA VLQALAFVTP
     GLRRASLPVD MDVISCSQKL RPQLKLAVKN LLKQTMRLCQ KVQQSSTLVQ PLQISHTRYG
     IFFNPLGMAY QDLSDAKSFY QQLSRSHLVL LPRPELGDDP FSSMPKVVQN YAAKGAIQYF
     LRQRVDNLDV FILDEENQLS HYVQAGSNMA ELVNKVSHHY VFDEHYASRA RFNIPQFFHL
     VRVAGELTVA PFGIDMSDQD TEF
//