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A9L1C2

- ASTE_SHEB9

UniProt

A9L1C2 - ASTE_SHEB9

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Protein
Succinylglutamate desuccinylase
Gene
astE, Sbal195_2198
Organism
Shewanella baltica (strain OS195)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity.UniRule annotation

Catalytic activityi

N-succinyl-L-glutamate + H2O = succinate + L-glutamate.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi63 – 631Zinc By similarity
Metal bindingi66 – 661Zinc By similarity
Metal bindingi160 – 1601Zinc By similarity
Active sitei224 – 2241 Reviewed prediction

GO - Molecular functioni

  1. hydrolase activity, acting on ester bonds Source: UniProtKB-HAMAP
  2. succinylglutamate desuccinylase activity Source: UniProtKB-EC
  3. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine catabolic process to glutamate Source: UniProtKB-HAMAP
  2. arginine catabolic process to succinate Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Arginine metabolism

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSBAL399599:GH6B-2260-MONOMER.
UniPathwayiUPA00185; UER00283.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinylglutamate desuccinylase (EC:3.5.1.96)
Gene namesi
Name:astE
Ordered Locus Names:Sbal195_2198
OrganismiShewanella baltica (strain OS195)
Taxonomic identifieri399599 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000000770: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 344344Succinylglutamate desuccinylaseUniRule annotation
PRO_1000083548Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi399599.Sbal195_2198.

Structurei

3D structure databases

ProteinModelPortaliA9L1C2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2988.
HOGENOMiHOG000280300.
KOiK05526.
OMAiTAPIEIC.
OrthoDBiEOG613070.

Family and domain databases

HAMAPiMF_00767. Arg_catab_AstE.
InterProiIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamiPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFiPIRSF017020. AstE. 1 hit.
TIGRFAMsiTIGR03242. arg_catab_astE. 1 hit.

Sequencei

Sequence statusi: Complete.

A9L1C2-1 [UniParc]FASTAAdd to Basket

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MLQALLDSKD FLALTLAHPE QFDSEFSFRL GDHTQVEVWD TGVIVFEPAQ    50
NEGKDVVLSC GVHGNETAPI ELCNGLIKQL LQQKIIAKQR TLFLIGNPLA 100
INNGTRIIDE NMNRLFSGEH SNPPGLVNPE RVRAKKLEAY IDRFYTAVAD 150
GRQRIHYDLH TAMRASKHEK FAIYPYRPGR AFSGEQIMFL AASGVDTVLF 200
HHEPTTTFSY FSSERYGADA FTIELGKVYP MGQNDMTRFI ATHEMFMRLI 250
TAKPLELDAF DADKVNLYQV CRVINKHFDD FEFTFATDVE NFRSFPKGFV 300
LAREGGQEIK VEHEFESVVF PNAKVPIGNR TVICLIPAVN ADVR 344
Length:344
Mass (Da):38,969
Last modified:February 5, 2008 - v1
Checksum:i10D217AF9EB4CD2F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000891 Genomic DNA. Translation: ABX49367.1.
RefSeqiYP_001554627.1. NC_009997.1.

Genome annotation databases

EnsemblBacteriaiABX49367; ABX49367; Sbal195_2198.
GeneIDi5753951.
KEGGisbn:Sbal195_2198.
PATRICi23470557. VBISheBal33754_2275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000891 Genomic DNA. Translation: ABX49367.1 .
RefSeqi YP_001554627.1. NC_009997.1.

3D structure databases

ProteinModelPortali A9L1C2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 399599.Sbal195_2198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX49367 ; ABX49367 ; Sbal195_2198 .
GeneIDi 5753951.
KEGGi sbn:Sbal195_2198.
PATRICi 23470557. VBISheBal33754_2275.

Phylogenomic databases

eggNOGi COG2988.
HOGENOMi HOG000280300.
KOi K05526.
OMAi TAPIEIC.
OrthoDBi EOG613070.

Enzyme and pathway databases

UniPathwayi UPA00185 ; UER00283 .
BioCyci SBAL399599:GH6B-2260-MONOMER.

Family and domain databases

HAMAPi MF_00767. Arg_catab_AstE.
InterProi IPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view ]
Pfami PF04952. AstE_AspA. 1 hit.
[Graphical view ]
PIRSFi PIRSF017020. AstE. 1 hit.
TIGRFAMsi TIGR03242. arg_catab_astE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OS195.

Entry informationi

Entry nameiASTE_SHEB9
AccessioniPrimary (citable) accession number: A9L1C2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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