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A9L0P6 (RLMI_SHEB9) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase I
EC=2.1.1.191
Alternative name(s):
23S rRNA m5C1962 methyltransferase
rRNA (cytosine-C(5)-)-methyltransferase RlmI
Gene names
Name:rlmI
Ordered Locus Names:Sbal195_3515
OrganismShewanella baltica (strain OS195) [Complete proteome] [HAMAP]
Taxonomic identifier399599 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA By similarity. HAMAP-Rule MF_01857

Catalytic activity

S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1962) in 23S rRNA. HAMAP-Rule MF_01857

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01857.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmI family.

Contains 1 PUA domain.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandRNA-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

rRNA (cytosine) methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396Ribosomal RNA large subunit methyltransferase I HAMAP-Rule MF_01857
PRO_0000366257

Regions

Domain2 – 7978PUA

Sequences

Sequence LengthMass (Da)Tools
A9L0P6 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 083A24D37511BB87

FASTA39644,143
        10         20         30         40         50         60 
MAIRIKLKPG REKSLERRHP WVFSNAIHNI KGKPEAGETV DVVAHDGHWL GRGAWSPESQ 

        70         80         90        100        110        120 
IQVRIWTFDR EEEIDREFFA RRLQRAQIGR NDLIREQGLT GYRLVAAESD GLPGITIDRY 

       130        140        150        160        170        180 
ANVLVCQLLS TGADLWRDTL VELLAEQYPD CAIYERSDVD SRKKEGLLPV TGLLHGTLPE 

       190        200        210        220        230        240 
MPVIIEENGI KIAVDVIKGH KTGFYLDQRD NRAIAARFVK DKSVLNCFCY TGTFGLYAAK 

       250        260        270        280        290        300 
AGAASIENVD VSSLALATAR LNMQVNGLSD DNVHYNEADV FKLLRLYRDE GKTFDVIVLD 

       310        320        330        340        350        360 
PPKFADNKAQ LNGACRGYKD INMIALQLLN PGGVLLTFSC SGLMPADLFQ KIVADAALDA 

       370        380        390 
KREIQFIERL SQASDHPIGS AFPEGFYLKG LVARAW

« Hide

References

[1]"Complete sequence of chromosome of Shewanella baltica OS195."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. expand/collapse author list , Brettar I., Rodrigues J., Konstantinidis K., Klappenbach J., Hofle M., Tiedje J., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS195.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000891 Genomic DNA. Translation: ABX50677.1.
RefSeqYP_001555937.1. NC_009997.1.

3D structure databases

ProteinModelPortalA9L0P6.
ModBaseSearch...

Protein-protein interaction databases

STRING399599.Sbal195_3515.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX50677; ABX50677; Sbal195_3515.
GeneID5755329.
KEGGsbn:Sbal195_3515.
PATRIC23473421. VBISheBal33754_3645.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1092.
HOGENOMHOG000266009.
KOK06969.
OMACSGLMTT.
ProtClustDBCLSK2462133.

Enzyme and pathway databases

BioCycSBAL399599:GH6B-3850-MONOMER.

Family and domain databases

HAMAPMF_01857. 23SrRNA_methyltr_I.
InterProIPR002478. PUA.
IPR015947. PUA-like_domain.
IPR023542. rRNA_lsu_MeTfrase_I.
IPR019614. SAM-dep_methyl-trfase.
[Graphical view]
PfamPF10672. Methyltrans_SAM. 1 hit.
[Graphical view]
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF88697. PUA-like. 1 hit.
PROSITEPS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLMI_SHEB9
AccessionPrimary (citable) accession number: A9L0P6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 5, 2008
Last modified: May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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