true2009-07-282024-03-2788BIOB_SHEB9Complete sequence of chromosome of Shewanella baltica OS195.Copeland A.Lucas S.Lapidus A.Barry K.Glavina del Rio T.Dalin E.Tice H.Pitluck S.Chain P.Malfatti S.Shin M.Vergez L.Schmutz J.Larimer F.Land M.Hauser L.Kyrpides N.Kim E.Brettar I.Rodrigues J.Konstantinidis K.Klappenbach J.Hofle M.Tiedje J.Richardson P.US DOE Joint Genome Institute2007-11EMBL/GenBank/DDBJNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]OS195Radical_SAMAldolase class IBioBAldolase_TIMBATS_domBiotin_synth/BioABBiotin_synthaseElp3/MiaA/NifB-like_rSAMrSAMbioBBIOTIN SYNTHASEBIOTIN SYNTHASE, MITOCHONDRIALBATSRadical_SAMBiotin_synthbiotin_synthaseRadical_SAMBATSElp3Radical SAM enzymesRADICAL_SAMBiotin synthase2.8.1.6bioBSbal195_1795Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.Homodimer.Belongs to the radical SAM superfamily. Biotin synthase family.Biotin synthase387831350Radical SAM core412685660631001311912634Fe-4S-S-AdoMet2008-02-05138783e79afc5ea1e21fd600c4d4c967a2d4bfMSQLQVRHDWKREEIEALFALPMNDLLFKAHSIHREVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKEKDMPYLKQMVQEVKALGMETCMTLGMLSEDQANDLASAGLDYYNHNLDTSPEYYGDVITTRTYQNRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLPQHPDSVPINMLVKVAGTPFEKLDDLDPLEFVRTIAVARILMPLSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEESDDMGLFRRLGLRPEQGAAAKLEEESAVLAKAAAYQDKSSAQFYDAGALtruetrue