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A9KXZ7 (RNPH_SHEB9) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease PH

Short name=RNase PH
EC=2.7.7.56
Alternative name(s):
tRNA nucleotidyltransferase
Gene names
Name:rph
Ordered Locus Names:Sbal195_0381
OrganismShewanella baltica (strain OS195) [Complete proteome] [HAMAP]
Taxonomic identifier399599 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP-Rule MF_00564

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP-Rule MF_00564

Sequence similarities

Belongs to the RNase PH family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA nucleotidyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA-specific ribonuclease activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Ribonuclease PH HAMAP-Rule MF_00564
PRO_1000082303

Sequences

Sequence LengthMass (Da)Tools
A9KXZ7 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: A3156168680FF6D4

FASTA23725,648
        10         20         30         40         50         60 
MRPSNRTPAQ TRPITITRQF TAHAEGSVLV EFGETKVLCT ASFTEGVPRF LKGQGQGWVT 

        70         80         90        100        110        120 
AEYGMLPRST HSRMDREAAR GKQSGRTQEI QRLIGRALRA CVDMKALGEN TIVIDCDVIQ 

       130        140        150        160        170        180 
ADGGTRTASI TGACVALVDA LNWARGKGII KSNPLKFLIA AVSVGIYKGE AISDLEYIED 

       190        200        210        220        230 
SAAETDMNVV MTETGKIIEI QGTAEGEPFS HEELLELLAL AKNSIREIVD VQKAALN 

« Hide

References

[1]"Complete sequence of chromosome of Shewanella baltica OS195."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. expand/collapse author list , Brettar I., Rodrigues J., Konstantinidis K., Klappenbach J., Hofle M., Tiedje J., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS195.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000891 Genomic DNA. Translation: ABX47562.1.
RefSeqYP_001552822.1. NC_009997.1.

3D structure databases

ProteinModelPortalA9KXZ7.
SMRA9KXZ7. Positions 2-236.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING399599.Sbal195_0381.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX47562; ABX47562; Sbal195_0381.
GeneID5752091.
KEGGsbn:Sbal195_0381.
PATRIC23466718. VBISheBal33754_0395.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0689.
HOGENOMHOG000229516.
KOK00989.
OMAKGQGWVT.
OrthoDBEOG6CZQQP.
ProtClustDBPRK00173.

Enzyme and pathway databases

BioCycSBAL399599:GH6B-399-MONOMER.

Family and domain databases

Gene3D3.30.230.70. 1 hit.
HAMAPMF_00564. RNase_PH.
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPH_SHEB9
AccessionPrimary (citable) accession number: A9KXZ7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families