Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A9KTL1

- NADK_SHEB9

UniProt

A9KTL1 - NADK_SHEB9

Protein

NAD kinase

Gene

nadK

Organism
Shewanella baltica (strain OS195)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.UniRule annotation

    Catalytic activityi

    ATP + NAD+ = ADP + NADP+.UniRule annotation

    Cofactori

    Divalent metal ions.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei89 – 891Proton acceptorUniRule annotation
    Binding sitei174 – 1741NADUniRule annotation
    Binding sitei191 – 1911NADUniRule annotation
    Binding sitei193 – 1931NADUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi89 – 902NADUniRule annotation
    Nucleotide bindingi163 – 1642NADUniRule annotation
    Nucleotide bindingi204 – 2096NADUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-HAMAP
    3. NAD+ kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. NAD metabolic process Source: InterPro
    2. NADP biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, NAD, NADP, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSBAL399599:GH6B-1415-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NAD kinaseUniRule annotation (EC:2.7.1.23UniRule annotation)
    Alternative name(s):
    ATP-dependent NAD kinaseUniRule annotation
    Gene namesi
    Name:nadKUniRule annotation
    Ordered Locus Names:Sbal195_1378
    OrganismiShewanella baltica (strain OS195)
    Taxonomic identifieri399599 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000000770: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309NAD kinasePRO_1000079511Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi399599.Sbal195_1378.

    Structurei

    3D structure databases

    ProteinModelPortaliA9KTL1.
    SMRiA9KTL1. Positions 21-309.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAD kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0061.
    HOGENOMiHOG000227221.
    KOiK00858.
    OMAiGAEFCLN.
    OrthoDBiEOG6PZXDR.

    Family and domain databases

    Gene3Di2.60.200.30. 1 hit.
    3.40.50.10330. 1 hit.
    HAMAPiMF_00361. NAD_kinase.
    InterProiIPR017438. ATP-NAD_kinase_dom_1.
    IPR016064. ATP-NAD_kinase_PpnK-typ.
    IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
    IPR002504. PolyP/ATP_NADK.
    [Graphical view]
    PANTHERiPTHR20275. PTHR20275. 1 hit.
    PfamiPF01513. NAD_kinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF111331. SSF111331. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A9KTL1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGINFDVSRP KARSSINMIT KFHTIGLIGK PHHQGTNQTL KRLHHWLTMQ    50
    GFEVLVEERV AAELGPNIEA VDLLEIGARC DLAIVVGGDG NMLGAARVLA 100
    RFDLGVIGVN RGNLGFLTDL PPDAFEEALA KVLDGEFDTE HRFLLEAEVY 150
    RHGMLKASNT AVNEAVLHPG KIAHMIEFEV YIDDQFMYSQ RADGMIVSTP 200
    TGSTAYALSA GGAILTPNLQ ALILVPMFPH TLSCRPIVVD ACSTIKMVVS 250
    PDNGENLEVS CDGHVHLAVL PGDEIIVRRS SERLRLIHPK GHNYFHVLRT 300
    KLGWGSKLF 309
    Length:309
    Mass (Da):33,871
    Last modified:February 5, 2008 - v1
    Checksum:iEC9445D16CFEBC91
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000891 Genomic DNA. Translation: ABX48552.1.
    RefSeqiYP_001553812.1. NC_009997.1.

    Genome annotation databases

    EnsemblBacteriaiABX48552; ABX48552; Sbal195_1378.
    GeneIDi5753107.
    KEGGisbn:Sbal195_1378.
    PATRICi23468834. VBISheBal33754_1434.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000891 Genomic DNA. Translation: ABX48552.1 .
    RefSeqi YP_001553812.1. NC_009997.1.

    3D structure databases

    ProteinModelPortali A9KTL1.
    SMRi A9KTL1. Positions 21-309.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399599.Sbal195_1378.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX48552 ; ABX48552 ; Sbal195_1378 .
    GeneIDi 5753107.
    KEGGi sbn:Sbal195_1378.
    PATRICi 23468834. VBISheBal33754_1434.

    Phylogenomic databases

    eggNOGi COG0061.
    HOGENOMi HOG000227221.
    KOi K00858.
    OMAi GAEFCLN.
    OrthoDBi EOG6PZXDR.

    Enzyme and pathway databases

    BioCyci SBAL399599:GH6B-1415-MONOMER.

    Family and domain databases

    Gene3Di 2.60.200.30. 1 hit.
    3.40.50.10330. 1 hit.
    HAMAPi MF_00361. NAD_kinase.
    InterProi IPR017438. ATP-NAD_kinase_dom_1.
    IPR016064. ATP-NAD_kinase_PpnK-typ.
    IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
    IPR002504. PolyP/ATP_NADK.
    [Graphical view ]
    PANTHERi PTHR20275. PTHR20275. 1 hit.
    Pfami PF01513. NAD_kinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF111331. SSF111331. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: OS195.

    Entry informationi

    Entry nameiNADK_SHEB9
    AccessioniPrimary (citable) accession number: A9KTL1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3