A9KQJ9 (A9KQJ9_CLOPH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259 RuleBase RU003981
EC=2.1.2.10 HAMAP MF_00259 RuleBase RU003981

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	Cphy_1538

Organism

Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) [Complete proteome] [HAMAP]

Taxonomic identifier

357809 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9KQJ9 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 33FEFFCCD95BC870	FASTA	360	40,773
	10 20 30 40 50 60 MELKTPLYEM HLKLHGKMVP FAGYLLPIQY EEGIIKEHMA VRTRAGIFDV SHMGEIRCSG 70 80 90 100 110 120 KDALRNLQQL LTNDFTDMSD GQARYSPMCN EQGGTVDDLI VYKKKEEEYL IVVNASNKEK 130 140 150 160 170 180 DYHWMLEHKF GEVVFEDISD KISQIALQGP KSQEILMKLS TDIPEKYYHA VFDGMVAGIP 190 200 210 220 230 240 CMISRTGYTG EDGFELYLDN TYAKTMWETL MEAGKEYGLI PCGLGARDTL RLEAGMPLYG 250 260 270 280 290 300 HEMNDEINPV ETGLSFAVKM QKEDFIGKDH LPDKDSLMRK RVGLRVTGRG IIREQEDVLV 310 320 330 340 350 360 DGKKVGFTTS GTHCPYLGYP VAMAILNKEY IKVGTKVTVI VRGREVEAEV VPLPFYKRTK

References

[1]

"Complete genome sequence of Clostridium phytofermentans ISDg." Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L., LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C. , Han C., Kuske C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.A., Richardson P. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000885 Genomic DNA. Translation: ABX41912.1.
RefSeq	YP_001558651.1. NC_010001.1.
3D structure databases
ProteinModelPortal	A9KQJ9.
ModBase	Search...
Protein-protein interaction databases
STRING	A9KQJ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5744360.
GenomeReviews	Gene locus Cphy_1538 in contig CP000885_GR.
KEGG	cpy:Cphy_1538.
PATRIC	19502702. VBICloPhy16213_1590.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	GPTLNAP.
ProtClustDB	CLSK978557.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9KQJ9_CLOPH

Accession

Primary (citable) accession number: A9KQJ9

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)