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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciCPHY357809:G1GAJ-2861-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Cphy_2771
OrganismiLachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans)
Taxonomic identifieri357809 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
Proteomesi
  • UP000000370 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000845751 – 307tRNA pseudouridine synthase BAdd BLAST307

Interactioni

Protein-protein interaction databases

STRINGi357809.Cphy_2771

Structurei

3D structure databases

ProteinModelPortaliA9KNW1
SMRiA9KNW1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A9KNW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGIINVYKE KGFTSFDVCA KLRGILKQKK IGHTGTLDPD AEGVLPVCVG
60 70 80 90 100
NATKLCDLLT DKDKVYEAVL TLGIITDTED MTGEVLERRL VTATYDRVLE
110 120 130 140 150
VVEQFTRTYD QIPPMYSAIK VNGQKLYELA RQGKVIERKP RTVTIHAIDI
160 170 180 190 200
LGVTPLEEQP EIVHEVRMRV SCSKGTYIRS LCRDIGEALQ CGGCMKSLIR
210 220 230 240 250
TQVSIFTLEN TLRLAEIEEC VKNQTLEQVL MPVDKLFLSM PKVVVKKESC
260 270 280 290 300
KFLYNGNQLV EDNFTWEKVS DQINIDKIRV YDSEDVFTGI YEYDEKKNCY

QPVKMFL
Length:307
Mass (Da):34,956
Last modified:February 5, 2008 - v1
Checksum:i24F2F430212C4E93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000885 Genomic DNA Translation: ABX43131.1
RefSeqiWP_012200782.1, NC_010001.1

Genome annotation databases

EnsemblBacteriaiABX43131; ABX43131; Cphy_2771
KEGGicpy:Cphy_2771

Similar proteinsi

Entry informationi

Entry nameiTRUB_LACP7
AccessioniPrimary (citable) accession number: A9KNW1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: April 25, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health