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Protein

Uronate isomerase

Gene

uxaC

Organism
Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciCPHY357809:GHCL-2785-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Cphy_2743
OrganismiClostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
Taxonomic identifieri357809 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
Proteomesi
  • UP000000370 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uronate isomerasePRO_1000082960Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi357809.Cphy_2743.

Structurei

3D structure databases

ProteinModelPortaliA9KNI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiITQVWLG.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A9KNI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPFMDKDFL LSTETAKTLY HDYAAQVPII DYHCHINPEE IAKDRSFDTI
60 70 80 90 100
TQVWLGGDHY KWRQMRSNGI DEKYITGDAS DIEKFEKWAE TLQKAIGNPL
110 120 130 140 150
YHWSHLELQR YFDYYGTLSA KTSEEVFKLC NEKLSQPEMS VRGLIKESNV
160 170 180 190 200
DTICTTDDPI DSLEWHKAIA KDSTFDVKVL PAWRPDKAMN LEKPDYLDYL
210 220 230 240 250
AKLESVSGVK IASFAGLMEA LKVRLEFFNS MGCKVSDHAL SYVMYKPATE
260 270 280 290 300
EEIEAIFAKR LAGGTISEME ELQFKTAFMV SVGREYNRLG WVMQLHYGTK
310 320 330 340 350
RDNNVFRFNQ LGADTGFDCI NTEGSSAELA NFLNALNSSD ELPKTIIYSL
360 370 380 390 400
NPTDNAAIGT VLGCFQDSTA VGKIQQGSAW WFNDNKTGMI DQMTSLANLG
410 420 430 440 450
LLANFVGMLT DSRSFLSYTR HEYFRRILCE LIGNWVENGE YPNDIEFLGQ
460
MVQDISYYNT KRYFGF
Length:466
Mass (Da):53,257
Last modified:February 5, 2008 - v1
Checksum:i94AF40F97C02D58A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000885 Genomic DNA. Translation: ABX43104.1.
RefSeqiWP_012200755.1. NC_010001.1.

Genome annotation databases

EnsemblBacteriaiABX43104; ABX43104; Cphy_2743.
KEGGicpy:Cphy_2743.
PATRICi19505240. VBICloPhy16213_2856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000885 Genomic DNA. Translation: ABX43104.1.
RefSeqiWP_012200755.1. NC_010001.1.

3D structure databases

ProteinModelPortaliA9KNI7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi357809.Cphy_2743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX43104; ABX43104; Cphy_2743.
KEGGicpy:Cphy_2743.
PATRICi19505240. VBICloPhy16213_2856.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiITQVWLG.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciCPHY357809:GHCL-2785-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_CLOPH
AccessioniPrimary (citable) accession number: A9KNI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.