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Protein

Xylose isomerase

Gene

xylA

Organism
Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCPHY357809:G1GAJ-1278-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Cphy_1219Imported
OrganismiLachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans)Imported
Taxonomic identifieri357809 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
Proteomesi
  • UP000000370 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi357809.Cphy_1219

Structurei

3D structure databases

ProteinModelPortaliA9KN98
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini108 – 284AP_endonuc_2InterPro annotationAdd BLAST177

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

A9KN98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNYFPNVPE VKYEGPNSTN PFAFKYYDAN KVVAGKTMKE HCRFALSWWH
60 70 80 90 100
TLCAGGADPF GVTTMDRTYG NITDPMELAK AKVDAGFELM TKLGIEFFCF
110 120 130 140 150
HDADIAPEGD TFEESKKNLF EIVDYIKEKM DQTGIKLLWG TANNFSHPRF
160 170 180 190 200
MHGASTSCNA DVFAYAAAKI KNALDATIKL GGKGYVFWGG REGYETLLNT
210 220 230 240 250
DLGLELDNMA RLMKMAVEYG RANGFDGDFY IEPKPKEPTK HQYDFDTATV
260 270 280 290 300
LAFLRKYGLE KDFKMNIEAN HATLAGHTFE HELAMARVNG AFGSVDANQG
310 320 330 340 350
DPNLGWDTDQ FPTDVHSATL AMLEVLKAGG FTNGGLNFDA KVRRGSFEFD
360 370 380 390 400
DIAYGYIAGM DTFALGLIKA AEIIDDGRIA KFVDDRYASY KTGIGKAIVD
410 420 430
GTTSLEELEQ YVLTHSEPVM QSGRQEVLET IVNNILFR
Length:438
Mass (Da):48,713
Last modified:February 5, 2008 - v1
Checksum:i4956BA939A41FE87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000885 Genomic DNA Translation: ABX41597.1
RefSeqiWP_012199251.1, NC_010001.1

Genome annotation databases

EnsemblBacteriaiABX41597; ABX41597; Cphy_1219
KEGGicpy:Cphy_1219

Similar proteinsi

Entry informationi

Entry nameiA9KN98_LACP7
AccessioniPrimary (citable) accession number: A9KN98
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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