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A9KMJ6 (UXUA_CLOPH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Cphy_1061
OrganismClostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) [Complete proteome] [HAMAP]
Taxonomic identifier357809 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Mannonate dehydratase HAMAP MF_00106
PRO_1000075898

Sequences

Sequence LengthMass (Da)Tools
A9KMJ6 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 12A4FBE0834F70F7

FASTA35840,930
        10         20         30         40         50         60 
MKMTFRWYGE GNDSITLKQI KQIPGCSGLM GVIDQYAAGE VWEESVIAEY VEHVHKAGLE 

        70         80         90        100        110        120 
VEVIESVNVH EDIKLGLPSR ELYIENYIKT IRNLAKHGIK VIVYNFMPVL DWLRTDLARV 

       130        140        150        160        170        180 
IEEDGSNSLY YDEEELLGLT PLQIVENTSK SSNGFTLPGW EPERLKELEN VLALYKNIDP 

       190        200        210        220        230        240 
DKLRENYKYF LEKVIPVCEE CGVKMAVHPD DPAWPIFGLP RIAHSEELFD KILELYDSES 

       250        260        270        280        290        300 
HTICLCTGSL GSNPENNIPE IIRHFGGKNR VGCFHVRNVK YLGYRKFRES SHLSSDGSLD 

       310        320        330        340        350 
MFEIMKAIHE TAPDTYIRPD HGRMIWDEVG RPGYGLYDRA LGIAYLNGIW EALEKSSK

« Hide

References

[1]"Complete genome sequence of Clostridium phytofermentans ISDg."
Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L., LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C. expand/collapse author list , Han C., Kuske C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.A., Richardson P.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700394 / DSM 18823 / ISDg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000885 Genomic DNA. Translation: ABX41441.1.
RefSeqYP_001558180.1. NC_010001.1.

3D structure databases

ProteinModelPortalA9KMJ6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9KMJ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5741897.
GenomeReviewsGene locus Cphy_1061 in contig CP000885_GR.
KEGGcpy:Cphy_1061.
PATRIC19501726. VBICloPhy16213_1103.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG585927.
OMADIKLGKP.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycCPHY357809:CPHY_1061-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_CLOPH
AccessionPrimary (citable) accession number: A9KMJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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