A9KME7 (A9KME7_CLOPH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 RuleBase RU000531
EC=2.5.1.19 HAMAP MF_00210 RuleBase RU000531

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	Cphy_2540

Organism

Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) [Complete proteome] [HAMAP]

Taxonomic identifier

357809 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 RuleBase RU000531
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210 RuleBase RU000531
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 RuleBase RU000531 EMBL ABX42901.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9KME7 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3D65AB2A7AD26A3B	FASTA	436	46,931
	10 20 30 40 50 60 MKFHKVKQIN GTLTVPGDKS ISHRAVMFGA IAEGTTEVYN FLKGADCLST IQCFRQLGIN 70 80 90 100 110 120 IEEDTKQQVI RIHGKGLHGL TPPSTILDVG NSGTTLRLIS GILSGQPFES NITGDSSIQK 130 140 150 160 170 180 RPMNRVITPL SLMNADIKSV LGNGCAPLCI NGSYQNGAKS ALKSIHYNSP IASAQVKSSI 190 200 210 220 230 240 LLAGLYAEGE TSVTEPYVSR NHTELMLQKF GANLSVNDKT VTIQPEPRLM AQKVHVPGDI 250 260 270 280 290 300 SSAAYFLAAA CILPNSELVI NNVGVNPTRD GIIDVLLAMG ADITKEDLKN QEGEAVCNLR 310 320 330 340 350 360 VRSSKLHGTV IEGSIIPRLI DEIPVIAVVA CFAEGDTIIK DAAELKVKES NRIDVMVQQL 370 380 390 400 410 420 KHMGANLTAT EDGMIIHGGQ KLSGTVIESK EDHRIAMSFA IASLMAEGET TIQGAECVNI 430 SYPEFYQDLY RLTCDN

References

[1]

"Complete genome sequence of Clostridium phytofermentans ISDg." Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L., LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C. , Han C., Kuske C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.A., Richardson P. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000885 Genomic DNA. Translation: ABX42901.1.
RefSeq	YP_001559640.1. NC_010001.1.
3D structure databases
ProteinModelPortal	A9KME7.
ModBase	Search...
Protein-protein interaction databases
STRING	A9KME7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5741818.
GenomeReviews	Gene locus Cphy_2540 in contig CP000885_GR.
KEGG	cpy:Cphy_2540.
PATRIC	19504810. VBICloPhy16213_2643.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646626.
OMA	GEDPRST.
ProtClustDB	CLSK2796458.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9KME7_CLOPH

Accession

Primary (citable) accession number: A9KME7

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)