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A9KL42

- TRPF_CLOPH

UniProt

A9KL42 - TRPF_CLOPH

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCPHY357809:GHCL-3916-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:Cphy_3844
OrganismiClostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Lachnoclostridium phytofermentans)
Taxonomic identifieri357809 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
ProteomesiUP000000370: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197095Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi357809.Cphy_3844.

Structurei

3D structure databases

ProteinModelPortaliA9KL42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A9KL42-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTKICGLKS LREIEIVNKY APNYVGFVFA GVKRKIDEEV ASLLRRELSS
60 70 80 90 100
EIQAVGVFVN ESIERIAKMC EKNTIQLVQL HGDEDRDYIN ALKLEVGAPI
110 120 130 140 150
IKAVRAQSVE QILEALTLPC DYFLYDTYSE HSYGGEGKRF DETILTEVYK
160 170 180 190 200
ESSNNEFKKY LQKPYFIAGG LTAQNVRLLD SRLEPYGVDV SSGVESMGQK
210
DEEKVKEFLF AAWRWNEN
Length:218
Mass (Da):24,895
Last modified:February 5, 2008 - v1
Checksum:iE02A3D72ACA435CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000885 Genomic DNA. Translation: ABX44191.1.
RefSeqiYP_001560930.1. NC_010001.1.

Genome annotation databases

EnsemblBacteriaiABX44191; ABX44191; Cphy_3844.
GeneIDi5744796.
KEGGicpy:Cphy_3844.
PATRICi19507599. VBICloPhy16213_4009.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000885 Genomic DNA. Translation: ABX44191.1 .
RefSeqi YP_001560930.1. NC_010001.1.

3D structure databases

ProteinModelPortali A9KL42.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357809.Cphy_3844.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX44191 ; ABX44191 ; Cphy_3844 .
GeneIDi 5744796.
KEGGi cpy:Cphy_3844.
PATRICi 19507599. VBICloPhy16213_4009.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CPHY357809:GHCL-3916-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700394 / DSM 18823 / ISDg.

Entry informationi

Entry nameiTRPF_CLOPH
AccessioniPrimary (citable) accession number: A9KL42
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3