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A9KL42

- TRPF_CLOPH

UniProt

A9KL42 - TRPF_CLOPH

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, Cphy_3844
Organism
Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCPHY357809:GHCL-3916-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:Cphy_3844
OrganismiClostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)
Taxonomic identifieri357809 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
ProteomesiUP000000370: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_1000197095Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi357809.Cphy_3844.

Structurei

3D structure databases

ProteinModelPortaliA9KL42.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A9KL42-1 [UniParc]FASTAAdd to Basket

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MKTKICGLKS LREIEIVNKY APNYVGFVFA GVKRKIDEEV ASLLRRELSS    50
EIQAVGVFVN ESIERIAKMC EKNTIQLVQL HGDEDRDYIN ALKLEVGAPI 100
IKAVRAQSVE QILEALTLPC DYFLYDTYSE HSYGGEGKRF DETILTEVYK 150
ESSNNEFKKY LQKPYFIAGG LTAQNVRLLD SRLEPYGVDV SSGVESMGQK 200
DEEKVKEFLF AAWRWNEN 218
Length:218
Mass (Da):24,895
Last modified:February 5, 2008 - v1
Checksum:iE02A3D72ACA435CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000885 Genomic DNA. Translation: ABX44191.1.
RefSeqiWP_012201839.1. NC_010001.1.
YP_001560930.1. NC_010001.1.

Genome annotation databases

EnsemblBacteriaiABX44191; ABX44191; Cphy_3844.
GeneIDi5744796.
KEGGicpy:Cphy_3844.
PATRICi19507599. VBICloPhy16213_4009.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000885 Genomic DNA. Translation: ABX44191.1 .
RefSeqi WP_012201839.1. NC_010001.1.
YP_001560930.1. NC_010001.1.

3D structure databases

ProteinModelPortali A9KL42.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357809.Cphy_3844.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX44191 ; ABX44191 ; Cphy_3844 .
GeneIDi 5744796.
KEGGi cpy:Cphy_3844.
PATRICi 19507599. VBICloPhy16213_4009.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CPHY357809:GHCL-3916-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700394 / DSM 18823 / ISDg.

Entry informationi

Entry nameiTRPF_CLOPH
AccessioniPrimary (citable) accession number: A9KL42
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 5, 2008
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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